González Míriam, Blanc Josep M, Pardo Jesús, Bosch Ramon, Viñuela José A
Servicio de Otorrinolaringología, Hospital de Tortosa Verge de la Cinta, Tarragona, España.
Acta Otorrinolaringol Esp. 2008 May;59(5):205-11.
Fine-needle aspiration (FNA) is a technique habitually used for the study of head and neck masses. This work evaluates the correlation between the cytological findings of the aspirations and the histological results observed after surgery. In addition, we set out the FNA protocol applied at our department.
We have conducted a retrospective study from 1990 to 2005 that includes 192 cases with head or neck masses. The true positives (TP), true negatives (TN), false positives (FP), false negatives (FN), sensitivity, specificity and the positive (PPV), and negative (NPV) predictive values of this test have been calculated.
Of the 192 patients included in this study surgery was performed in 172 cases, for whom the cytohistological correlation was determined. The FNA was negative for malignant cells in 107 cases and positive in 60 cases. In 5 of the 172 cases FNA was not indicative. After the surgery, benignancy was confirmed in 104 of the 107 cases thus giving 3 FN and malignancy was confirmed in 58 of the 60 cases, i.e. 2 FP. With these data, the sensitivity obtained was 95.08 %, specificity was 98.11 %, while PPV was 96.67 % and NPV 97.20 %.
In the light of the results, FNA is a very useful method in the diagnostic work-up of head and neck masses.
细针穿刺抽吸术（FNA）是一种常用于头颈部肿块研究的技术。本研究评估穿刺抽吸的细胞学检查结果与术后观察到的组织学结果之间的相关性。此外，我们阐述了本科室应用的FNA方案。
我们进行了一项回顾性研究，时间跨度为1990年至2005年，纳入192例头颈部肿块患者。计算了该检测的真阳性（TP）、真阴性（TN）、假阳性（FP）、假阴性（FN）、敏感性、特异性以及阳性预测值（PPV）和阴性预测值（NPV）。
本研究纳入的192例患者中，172例接受了手术，并确定了细胞组织学相关性。FNA检查结果显示，107例恶性细胞呈阴性，60例呈阳性。172例中有5例FNA结果不具指示性。术后，107例中的104例被确认为良性，即3例假阴性；60例中的58例被确认为恶性，即2例假阳性。根据这些数据，获得的敏感性为95.08%，特异性为98.11%，PPV为96.67%，NPV为97.20%。
根据研究结果，FNA在头颈部肿块的诊断检查中是一种非常有用的方法。
