Sweets Thomas, Bracken R Bruce, Geisler Eric J, Warnick Ronald
Division of Urology, Department of Surgery, University of Cincinnati, Cincinnati, Ohio 45267, USA.
Urology. 2009 Mar;73(3):681.e7-9. doi: 10.1016/j.urology.2008.03.025. Epub 2008 May 27.
Solitary metastasis to the brain from prostate cancer is rare. We present a young patient with a prostate-specific antigen value of 26 ng/dL and pathologic Gleason score 4 + 5 = 9 prostatic adenocarcinoma who developed a solitary cerebral metastasis 4 years after radical prostatectomy. With aggressive treatment involving resection of the solitary metastasis and use of local brachytherapy, the patient remains with an undetectable PSA level and without evidence of disease 5 years later. Our experience suggests that delayed solitary metastasis may be curable with treatment.
前列腺癌孤立性脑转移罕见。我们报告一名年轻患者，其前列腺特异性抗原值为26 ng/dL，病理Gleason评分4 + 5 = 9，为前列腺腺癌，在根治性前列腺切除术后4年发生孤立性脑转移。通过积极治疗，包括切除孤立性转移灶和使用局部近距离放疗，该患者5年后前列腺特异性抗原水平检测不到，且无疾病证据。我们的经验表明，延迟性孤立性转移经治疗可能治愈。
