Ruiz-Roldán M Carmen, Garre Victoriano, Guarro Josep, Mariné Marçal, Roncero M Isabel G
Departamento de Genética, Universidad de Córdoba, Edificio Gregor Mendel, Campus de Rabanales, E14071 Córdoba, Spain.
Eukaryot Cell. 2008 Jul;7(7):1227-30. doi: 10.1128/EC.00072-08. Epub 2008 May 23.
Knockout mutants of Fusarium oxysporum lacking the putative photoreceptor Wc1 were impaired in aerial hyphae, surface hydrophobicity, light-induced carotenogenesis, photoreactivation after UV treatment, and upregulation of photolyase gene transcription. Infection experiments with tomato plants and immunodepressed mice revealed that Wc1 is dispensable for pathogenicity on plants but required for full virulence on mammals.
缺乏假定光感受器Wc1的尖孢镰刀菌基因敲除突变体在气生菌丝、表面疏水性、光诱导类胡萝卜素生成、紫外线处理后的光复活以及光解酶基因转录上调方面存在缺陷。对番茄植株和免疫抑制小鼠进行的感染实验表明,Wc1对于植物致病性并非必需,但对哺乳动物的完全毒力却是必需的。