Tanaka Tatsurou, Ono Kentaro, Ansai Toshihiro, Yoshioka Izumi, Habu Manabu, Tomoyose Taiki, Yamashita Yoshihiro, Nishida Ikuko, Oda Masafumi, Kuroiwa Hirohito, Wakasugi-Sato Nao, Okabe Sachiko, Kito Shinji, Takahashi Tetsu, Tominaga Kazuhiro, Inenaga Kiyotoshi, Morimoto Yasuhiro
Department of Oral Diagnostic Science, Kyushu Dental Collage, Kitakyushu, Japan.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008 Jul;106(1):115-23. doi: 10.1016/j.tripleo.2008.03.012. Epub 2008 May 27.
The aim was to evaluate the utility of dynamic magnetic resonance (MR) sialographic images as a diagnostic tool for patients with xerostomia as chief complaint.
Various parameters of dynamic MR sialographic images from 40 healthy volunteers were compared with those from 28 patients having dry mouth as chief complaint. Dynamic MR sialographic images were acquired using a 1.5-T full-body MR system and 2-dimensional fast asymmetric spin-echo (2D-FASE) sequences. Acquisition of the optimal section using 2D-FASE sequencing with single-section acquisition of thick sections was repeated every 30 s before and after a few drops of 5% citric acid was placed on the tongue. Student t test was used to examine differences between the healthy volunteer and patient groups regarding the maximum area of salivary gland ducts before and after citric acid stimulation.
The maximum area of the detectable ducts in the patient group was significantly smaller (P < 0.001), whereas the change in detectable duct area was significantly lower (P < 0.001).
This study suggests that dynamic MR sialographic images and data can be useful in the diagnosis of patients with dry mouth as chief complaint.
旨在评估动态磁共振(MR)涎管造影图像作为以口干为主诉患者的诊断工具的效用。
将40名健康志愿者的动态MR涎管造影图像的各项参数与28名以口干为主诉的患者的参数进行比较。使用1.5-T全身MR系统和二维快速不对称自旋回波(2D-FASE)序列获取动态MR涎管造影图像。在舌上滴几滴5%柠檬酸之前和之后,每隔30秒重复使用2D-FASE序列进行单厚层采集以获取最佳层面。采用学生t检验来检查健康志愿者组和患者组在柠檬酸刺激前后涎腺导管最大面积方面的差异。
患者组中可检测导管的最大面积显著更小(P < 0.001),而可检测导管面积的变化显著更低(P < 0.001)。
本研究表明,动态MR涎管造影图像和数据可有助于诊断以口干为主诉的患者。