Krepel C J, Gohr C M, Edmiston C E, Farmer S G
Surgical Microbiology Research Laboratory, Medical College of Wisconsin, Milwaukee 53226.
J Infect Dis. 1991 May;163(5):1148-50. doi: 10.1093/infdis/163.5.1148.
Fifty isolates of Peptostreptococcus magnus from intraabdominal sepsis, nonpuerperal breast abscess, and diabetic foot infections were examined for collagenase activity using bovine type I collagen. Collagenase production was detected in a higher percentage of strains from nonpuerperal breast and diabetic foot specimens (P less than .001). This enzyme may be responsible for P. magnus playing a more central role in the pathogenesis of nonpuerperal breast abscess and diabetic foot disease than in intraabdominal sepsis.
使用牛I型胶原蛋白对50株来自腹腔内脓毒症、非产褥期乳房脓肿和糖尿病足感染的巨大消化链球菌分离株进行胶原酶活性检测。在非产褥期乳房和糖尿病足标本中，检测到产生胶原酶的菌株比例更高（P小于0.001）。这种酶可能是巨大消化链球菌在非产褥期乳房脓肿和糖尿病足疾病的发病机制中比在腹腔内脓毒症中发挥更核心作用的原因。
