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炎症生物标志物在预测代谢综合征中的能力

[Inflammation biomarkers capacity in predicting the metabolic syndrome].

作者信息

Volp Ana Carolina Pinheiro, Alfenas Rita de Cássia G, Costa Neuza Maria Brunoro, Minim Valéria Paula Rodrigues, Stringueta Paulo César, Bressan Josefina

机构信息

Departamento de Ciência e Tecnologia dos Alimentos, Universidade Federal de Viçosa, MG, Brasil.

出版信息

Arq Bras Endocrinol Metabol. 2008 Apr;52(3):537-49. doi: 10.1590/s0004-27302008000300015.

DOI:10.1590/s0004-27302008000300015
PMID:18506280
Abstract

The inflammatory process is the link between metabolic syndrome and cardiovascular diseases. To measure the degree of subclinical inflammation some inflammatory biomarkers have been considered. This work reviews the recent researches of the associations between inflammatory biomarkers and metabolic syndrome, as well as the capacity in predicting the metabolic syndrome. These biomarkers include pro-inflammatory cytokines, anti-inflammatory cytokines, adipokines, chemokines, inflammation markers derived from hepatocites, the consequence markers of inflammation and enzymes. This review integrates the new knowledge of inflammatory mediators interactions with metabolic syndrome, since these biomarkers play different roles and follow diverse metabolic ways.

摘要

炎症过程是代谢综合征与心血管疾病之间的联系。为了衡量亚临床炎症的程度,人们考虑了一些炎症生物标志物。本文综述了炎症生物标志物与代谢综合征之间关联的最新研究,以及其预测代谢综合征的能力。这些生物标志物包括促炎细胞因子、抗炎细胞因子、脂肪因子、趋化因子、源自肝细胞的炎症标志物、炎症后果标志物和酶。由于这些生物标志物发挥着不同作用并遵循不同代谢途径,本综述整合了炎症介质与代谢综合征相互作用的新知识。

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