Stocchetti Nino, Citerio Giuseppe, Maas Andrew, Andrews Peter, Teasdale Graham
Neuroscience Intensive Care Unit, University of Milan, Ospedale Maggiore Policlinico, Mangiagalli, e Regina Elena, Fondazione IRCCS, Milan, Italy.
Intensive Care Med. 2008 Oct;34(10):1774-8. doi: 10.1007/s00134-008-1168-7. Epub 2008 May 28.
William Bryan Jennett, one of the leading figures in neurosurgery of the twentieth century, has died on 26 January 2008, at the age of 81. He made fundamental contributions to the field of traumatic brain injury (TBI) that still shape diagnosis, management and prognosis worldwide, in the second part of the last century. This paper is meant to gratefully acknowledge his contributions and to reflect on the implications that his work has for neurointensive care today. Starting from his early steps, we tried to highlight his fundamental work on diagnosis of severity in TBI, on rescue, treatment and prognosis of severe TBI. Moreover, his contribution in the definition of vegetative state, minimally conscious state and brain death has been emphasized. The contribution of Professor Bryan Jennett was in fact seminal in many aspects: the application of a common language in brain damage evaluation, where GCS and GOS are now universally employed; a critical approach to TBI diagnosis and treatment, in the search of proven better therapies; a quantitative approach to TBI prognosis, based on large clinical series and appropriate statistics; a strong commitment to the ethical implication of survival after severe injury, including the vegetative status; social responsibility in the diagnosis of brain death and in organ donors procurement. For these reasons, he can be considered one of the leading figures in neurosurgery and neurology of the twentieth century. This paper is meant to gratefully acknowledge his contributions and to reflect on the implications that his work has for neuro-intensive care today.
威廉·布莱恩·詹尼特是20世纪神经外科领域的领军人物之一，于2008年1月26日辞世，享年81岁。上世纪下半叶，他在创伤性脑损伤（TBI）领域做出了根本性贡献，至今仍影响着全球范围内对TBI的诊断、治疗和预后判断。本文旨在衷心感谢他的贡献，并思考他的工作对当今神经重症监护的启示。从他的早期工作开始，我们试图突出他在TBI严重程度诊断、重症TBI的救治、治疗及预后方面的基础性工作。此外，还强调了他在植物状态、微意识状态及脑死亡定义方面的贡献。布莱恩·詹尼特教授的贡献在诸多方面都具有开创性：在脑损伤评估中应用通用语言，如今格拉斯哥昏迷量表（GCS）和格拉斯哥预后量表（GOS）已被广泛使用；对TBI诊断和治疗采取批判性方法，探寻经证实的更好治疗方法；基于大量临床病例系列和恰当统计数据的TBI预后定量方法；对严重损伤后生存的伦理影响，包括植物状态的坚定关注；在脑死亡诊断及器官捐献者获取方面的社会责任。基于这些原因，他可被视为20世纪神经外科和神经学领域的领军人物之一。本文旨在衷心感谢他的贡献，并思考他的工作对当今神经重症监护的启示。
