Xiu R, Berglund O
Zhonghua Yi Xue Za Zhi. 1991 Jan;71(1):18-20, 4.
CCTV-microscopic observation of nail-fold microcirculation was made on 11 AIDS patients and 11 healthy European adults. Unique severe microcirculatory disturbances were observed in these patients: (1) severe dysfunction of automatic alternative capillary blood flow perfusion. All the capillary loops in the same microscopic field emptied at the same moment and remained empty for a long time (3-100 seconds). Subsequent filling up of the capillary loops was very slow (1-2.5 min/loop). (2) remarkable damage of endothelial cells in the capillary wall. Some parts of the capillary wall were penetrated by some heterogeneous, visible and sludgy mass, making the wall swelled and the lumen narrowed. The wall tension in all the capillaries was markedly decreased. After the capillary loops had emptied, these damaged parts of the wall still remained in the field. These findings demonstrated the deep involvement of microcirculation in the pathogenesis of AIDS, and also showed the close relationship between microcirculation and the immune condition of the organism.
对11例艾滋病患者和11名欧洲健康成年人进行了央视显微镜下甲襞微循环观察。在这些患者中观察到独特的严重微循环障碍：（1）自动交替性毛细血管血流灌注严重功能障碍。同一显微镜视野内的所有毛细血管袢同时排空并长时间保持空虚状态（3 - 100秒）。随后毛细血管袢的充盈非常缓慢（1 - 2.5分钟/袢）。（2）毛细血管壁内皮细胞明显受损。毛细血管壁的某些部分被一些异质性、可见的、淤滞的物质穿透，使管壁肿胀，管腔狭窄。所有毛细血管的壁张力明显降低。在毛细血管袢排空后，这些受损的管壁部分仍留在视野中。这些发现表明微循环在艾滋病发病机制中深度参与，也显示了微循环与机体免疫状况之间的密切关系。
