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在刚果民主共和国,美拉胂醇治疗昏睡病的失败率很高。

High failure rates of melarsoprol for sleeping sickness, Democratic Republic of Congo.

作者信息

Robays Jo, Nyamowala Gaspard, Sese Claude, Betu Ku Mesu Kande Victor, Lutumba Pascal, Van der Veken Wim, Boelaert Marleen

机构信息

Institute of Tropical Medicine, Antwerp, Belgium.

出版信息

Emerg Infect Dis. 2008 Jun;14(6):966-7. doi: 10.3201/eid1406.071266.

DOI:10.3201/eid1406.071266
PMID:18507916
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2600279/
Abstract

A retrospective chart review of 4,925 human African trypanosomiasis patients treated with melarsoprol in 2001-2003 in Equateur Nord Province of the Democratic Republic of Congo showed a treatment failure rate of 19.5%. This rate increased over the 3 years. Relapse rates were highest in the central part of the province.

摘要

对2001年至2003年在刚果民主共和国赤道北省接受美拉胂醇治疗的4925例人类非洲锥虫病患者进行的回顾性病历审查显示,治疗失败率为19.5%。该比率在3年中有所上升。该省中部的复发率最高。

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本文引用的文献

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Eflornithine is a cost-effective alternative to melarsoprol for the treatment of second-stage human West African trypanosomiasis in Caxito, Angola.依氟鸟氨酸是治疗安哥拉卡希托市第二阶段人类西非锥虫病的一种具有成本效益的替代药物,可替代美拉胂醇。
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