Roe R Michael, Donohue Kevin V, Khalil Sayed M S, Sonenshine Daniel E
Department of Entomology, North Carolina State University, Raleigh, North Carolina 27695-7647, USA.
Front Biosci. 2008 May 1;13:7250-68. doi: 10.2741/3226.
The presence of a "status quo" hormone like JH has not been found in ticks. The most advanced understanding of tick endocrinology is associated with female reproduction, where the sequence of the first messages for storage proteins (vitellogenin (Vg) and carrier protein), the Vg receptor, and male peptidic pheromones were recently reported. The current consensus model suggests that ecdysteroids from the epidermis regulated by a putative peptidic ecdysiotrophic hormone from the synganlion initiates the expression of the Vg messages in fat body and midgut. Vg protein, secreted into the hemolymph, requires an ovary Vg receptor to be absorbed by oocytes. Male pheromones transferred into the female genital tract during mating initiate blood feeding to repletion and vitellogenesis. The work so far on tick endocrinology is limited by the paucity of identified hormones and the small number of studies on a few tick models. The role of storage proteins in the evolution of hematophagy is discussed.
在蜱虫中尚未发现像保幼激素这样的“维持现状”激素。对蜱虫内分泌学的最前沿理解与雌性繁殖相关，最近有报道称，储存蛋白（卵黄原蛋白（Vg）和载体蛋白）、Vg受体以及雄性肽类信息素的首个信使的序列。目前的共识模型表明，来自表皮的蜕皮甾体受来自神经节的一种假定的肽类促蜕皮激素调控，从而启动脂肪体和中肠中Vg信使的表达。分泌到血淋巴中的Vg蛋白需要卵巢Vg受体才能被卵母细胞吸收。交配期间转移到雌性生殖道中的雄性信息素会促使其吸血直至饱足并启动卵黄生成。目前关于蜱虫内分泌学的研究受到已鉴定激素数量稀少以及对少数蜱虫模型研究较少的限制。文中还讨论了储存蛋白在吸血进化中的作用。
