Sendagorta Elena, Pizarro Angel, Feito Marta, Mayor Matias, Ramírez Paloma, Floristan Uxua, Feltes Rosa
Dermatology Department, University Hospital La Paz, Madrid.
ScientificWorldJournal. 2008 May 23;8:556-7. doi: 10.1100/tsw.2008.78.
We present a female patient who developed mucosal and skin hyperpigmentation due to metastatic malignant melanoma. Diffuse cutaneous melanosis is a rare entity that complicates a small percentage of metastatic melanomas, confering a fatal prognosis. We discuss briefly the current evidence on pathogenesis of melanosis arising from metastatic melanoma.
我们报告了一名因转移性恶性黑色素瘤而出现黏膜和皮肤色素沉着过度的女性患者。弥漫性皮肤黑变病是一种罕见的病症，在一小部分转移性黑色素瘤中出现并发症，预后不佳。我们简要讨论了目前关于转移性黑色素瘤引起黑变病发病机制的证据。
