Steiner A, Rappersberger K, Groh V, Pehamberger H
Department of Dermatology I, University of Vienna Medical School, Austria.
J Am Acad Dermatol. 1991 Apr;24(4):625-8. doi: 10.1016/0190-9622(91)70096-k.
The skin of a patient with diffuse melanosis as a result of malignant melanoma was examined by light microscopy, immunohistochemistry, and electron microscopy. Our findings indicate that the slate-blue discoloration in this patient was due to pigment deposition in dermal macrophages and endothelial cells. Multiple attempts to identify disseminated metastatic melanoma cells were unsuccessful.
对一名因恶性黑色素瘤导致弥漫性黑变病患者的皮肤进行了光学显微镜、免疫组织化学和电子显微镜检查。我们的研究结果表明，该患者的蓝灰色变色是由于真皮巨噬细胞和内皮细胞中的色素沉积所致。多次尝试鉴定播散性转移性黑色素瘤细胞均未成功。
