Schroner Z, Lazurova I, Petrovicova J
NZZ Internal and Diabetes Out-patient Clinic, Moldava nad Bodvou, Slovakia.
Bratisl Lek Listy. 2008;109(3):125-9.
Autoimmune thyroid diseases are frequent in patients with type 1 diabetes mellitus. The aim of our study was to determine the incidence of autoimmune thyroid diseases (AIT) in the different groups of patients with DM (DM type 1--classical form, DM type 1--subtype LADA, DM type 2) and compare the incidence of AIT among the groups as well as to the control group of non-diabetics. We also focused our attention on the factors that influence the risk of thyroid diseases incidence in diabetics.
We examined 79 diabetics (38 women and 41 men, x = 55.4 +/- 2.8). Diabetic patients were divided into three groups. The control group consisted of 30 non-diabetics.
Chronic autoimmune thyroiditis was diagnosed in 8 (40%) patients in the first group, in 6 (50%) in the 2nd group of patients and finally in 20 (43%) patients with type 2 diabetes mellitus--3rd group. A significantly higher prevalence of chronic autoimmune thyroiditis was observed in female diabetics and in diabetics with positive family history of thyroid diseases.
Results of paper confirm an increased prevalence of chronic autoimmune thyroiditis in patients with all types of diabetes mellitus resulting in recommendation of careful follow-up of all diabetic patients for presence of thyroid autoimmunity (Tab. 5, Ref, 13). Full Text (Free, PDF) www.bmj.sk.
自身免疫性甲状腺疾病在1型糖尿病患者中很常见。我们研究的目的是确定不同糖尿病患者组（1型糖尿病——经典型、1型糖尿病——成人隐匿性自身免疫糖尿病亚型、2型糖尿病）中自身免疫性甲状腺疾病（AIT）的发病率，并比较各组以及与非糖尿病对照组之间AIT的发病率。我们还关注了影响糖尿病患者甲状腺疾病发病风险的因素。
我们检查了79名糖尿病患者（38名女性和41名男性，平均年龄 = 55.4 ± 2.8岁）。糖尿病患者分为三组。对照组由30名非糖尿病患者组成。
第一组中有8名（40%）患者被诊断为慢性自身免疫性甲状腺炎，第二组中有6名（50%）患者，最后在2型糖尿病患者的第三组中有20名（43%）患者。在女性糖尿病患者和有甲状腺疾病家族史阳性的糖尿病患者中，慢性自身免疫性甲状腺炎的患病率明显更高。
本文结果证实所有类型糖尿病患者中慢性自身免疫性甲状腺炎的患病率增加，因此建议对所有糖尿病患者进行仔细随访，以检查是否存在甲状腺自身免疫（表5，参考文献13）。全文（免费，PDF格式）www.bmj.sk 。
