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头部覆盖物与婴儿猝死综合征风险:来自新西兰和德国婴儿猝死综合征病例对照研究的结果

Head covering and the risk for SIDS: findings from the New Zealand and German SIDS case-control studies.

作者信息

Mitchell Edwin A, Thompson John M D, Becroft David M O, Bajanowski Thomas, Brinkmann Bernd, Happe Arusha, Jorch Gerhard, Blair Peter S, Sauerland Cristina, Vennemann Mechtild M

机构信息

University of Auckland, Department of Paediatrics, Private Bag 92019, Auckland, New Zealand.

出版信息

Pediatrics. 2008 Jun;121(6):e1478-83. doi: 10.1542/peds.2007-2749.

Abstract

OBJECTIVES

The aim of this investigation was to identify risk factors for being found with the head covered in sudden infant death syndrome cases and determine whether head covering was likely to be an agonal event or potentially part of the causal pathway in some cases. By using the data from 2 sudden infant death syndrome case-control studies, consistency of the findings could be assessed.

METHODS

Two case-control studies were assessed: (1) the New Zealand Cot Death Study (1987-1990, 393 sudden infant death syndrome cases) and (2) a German SIDS case-control study (1998-2001, 333 sudden infant death syndrome cases).

RESULTS

The proportion of sudden infant death syndrome cases in which infants were found with their head covered was 15.6% in the New Zealand study and 28.1% in the German study. Being found with head covering was associated with older infant age. In both studies, being found with head covering was associated with being very sweaty when found. Head covering was also associated with the incidence and severity of thymic petechiae in both studies. Both the position in which the child was placed to sleep and the position in which the child was found were not associated with head covering.

CONCLUSIONS

The finding that sudden infant death syndrome cases in which infants were found with their heads covered were often very sweaty suggests that head covering was not an agonal event and that it preceded the death and may have been causally related to the death. Infants who were found with their head covered were older, which probably reflects motor development.

摘要

目的

本调查旨在确定婴儿猝死综合征病例中被发现头部覆盖的风险因素,并确定头部覆盖在某些情况下是可能为濒死事件还是潜在因果途径的一部分。通过使用两项婴儿猝死综合征病例对照研究的数据,可以评估研究结果的一致性。

方法

评估了两项病例对照研究:(1)新西兰婴儿床死亡研究(1987 - 1990年,393例婴儿猝死综合征病例)和(2)一项德国婴儿猝死综合征病例对照研究(1998 - 2001年,333例婴儿猝死综合征病例)。

结果

在新西兰的研究中,被发现头部覆盖的婴儿猝死综合征病例比例为15.6%,在德国的研究中为28.1%。被发现头部覆盖与较大婴儿年龄相关。在两项研究中,被发现头部覆盖均与被发现时出汗很多有关。在两项研究中,头部覆盖也与胸腺瘀点的发生率和严重程度相关。孩子睡觉的姿势和被发现时的姿势均与头部覆盖无关。

结论

婴儿猝死综合征病例中被发现头部覆盖的婴儿往往出汗很多,这一发现表明头部覆盖不是濒死事件,它在死亡之前发生,并且可能与死亡存在因果关系。被发现头部覆盖的婴儿年龄较大,这可能反映了运动发育情况。

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