da Silva Filho Fernando Palma, Marchiori Edson, Valiante Paulo Marcos, Escuissato Dante L, Gasparetto Taisa Davaus
Department of Radiology, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
J Thorac Imaging. 2008 May;23(2):135-7. doi: 10.1097/RTI.0b013e31815a662d.
Kaposi sarcoma (KS) is a fulminate and disseminated form of acquired immunodeficiency syndrome (AIDS)-defining neoplasm, usually presenting pulmonary involvement. We report a 40-year-old woman with AIDS and biopsy-proven KS showing unusual high-resolution computed tomography (HRCT) findings. HRCT showed areas of ground-glass attenuation with superimposed septal thickening ("crazy-paving" pattern). CT-pathologic correlation revealed that crazy-paving pattern in this case was due to accompanying pulmonary edema and hemorrhage in addition to tumor cell infiltration into the peribronchovascular interstitium, interlobular and alveolar septa. The authors suggest the inclusion of KS in the differential diagnosis of lung diseases in patients with AIDS presenting with crazy-paving pattern on the HRCT.
卡波西肉瘤（KS）是获得性免疫缺陷综合征（AIDS）定义性肿瘤的一种暴发性和播散性形式，通常累及肺部。我们报告一名40岁患有AIDS且经活检证实为KS的女性，其高分辨率计算机断层扫描（HRCT）表现异常。HRCT显示磨玻璃样衰减区域伴有小叶间隔增厚（“铺路石征”）。CT与病理对照显示，本例中的铺路石征是由于除肿瘤细胞浸润到支气管血管周围间质、小叶间隔和肺泡间隔外，还伴有肺水肿和出血。作者建议，对于HRCT上表现为铺路石征的AIDS患者，在肺部疾病的鉴别诊断中应考虑KS。
