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用于计算兔子在2.45吉赫兹全身暴露下核心体温升高的计算模型。

Computational model for calculating body-core temperature elevation in rabbits due to whole-body exposure at 2.45 GHz.

作者信息

Hirata Akimasa, Sugiyama Hironori, Kojima Masami, Kawai Hiroki, Yamashiro Yoko, Fujiwara Osamu, Watanabe Soichi, Sasaki Kazuyuki

机构信息

Nagoya Institute of Technology, Japan.

出版信息

Phys Med Biol. 2008 Jun 21;53(12):3391-404. doi: 10.1088/0031-9155/53/12/022. Epub 2008 Jun 3.

DOI:10.1088/0031-9155/53/12/022
PMID:18523344
Abstract

In the current international guidelines and standards with regard to human exposure to electromagnetic waves, the basic restriction is defined in terms of the whole-body average-specific absorption rate. The rationale for the guidelines is that the characteristic pattern of thermoregulatory response is observed for the whole-body average SAR above a certain level. However, the relationship between energy absorption and temperature elevation was not well quantified. In this study, we improved our thermal computation model for rabbits, which was developed for localized exposure on eye, in order to investigate the body-core temperature elevation due to whole-body exposure at 2.45 GHz. The effect of anesthesia on the body-core temperature elevation was also discussed in comparison with measured results. For the whole-body average SAR of 3.0 W kg(-1), the body-core temperature in rabbits elevates with time, without becoming saturated. The administration of anesthesia suppressed body-core temperature elevation, which is attributed to the reduced basal metabolic rate.

摘要

在当前关于人类暴露于电磁波的国际指南和标准中,基本限制是根据全身平均比吸收率来定义的。这些指南的基本原理是,当全身平均比吸收率高于某一水平时,会观察到体温调节反应的特征模式。然而,能量吸收与体温升高之间的关系并未得到很好的量化。在本研究中,我们改进了我们为眼部局部暴露而开发的兔子热计算模型,以研究2.45 GHz全身暴露引起的体核温度升高。与测量结果相比,还讨论了麻醉对体核温度升高的影响。对于3.0 W kg(-1)的全身平均比吸收率,兔子的体核温度随时间升高,且不会饱和。麻醉的使用抑制了体核温度升高,这归因于基础代谢率的降低。

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