Metcalfe David
The Subwarden, Cryfield 3, University of Warwick Coventry, West Midlands, United Kingdom.
Mcgill J Med. 2008 Jan;11(1):51-7.
Osteoporotic hip fractures have a profound impact on the physical health and psychosocial wellbeing of patients. In addition, osteoporosis has considerable economic implications and is projected to become an increasing burden on developed economies over the coming decades. Nevertheless, the risk factors for both osteoporosis and hip fracture are both well understood and preventable, often with only minor lifestyle changes. This narrative review explores the pathological process underlying osteoporosis and considers how each of the major risk factors contributes to the pathology of this disease. It is hoped that a greater understanding of individual risk factors will result in renewed efforts to promote increased bone density before patients present with hip fracture.
骨质疏松性髋部骨折对患者的身体健康和心理社会福祉有着深远影响。此外,骨质疏松症具有相当大的经济影响,预计在未来几十年将给发达经济体带来日益沉重的负担。然而,骨质疏松症和髋部骨折的风险因素都已为人熟知且可预防,通常只需对生活方式稍作改变。本叙述性综述探讨了骨质疏松症的病理过程,并思考了各主要风险因素如何促成该疾病的病理变化。希望对个体风险因素有更深入的了解,能促使人们在患者发生髋部骨折之前,重新努力提高骨密度。