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前交叉韧带重建:人工假体的回顾——过去、现在与可能的未来

Anterior cruciate ligament reconstruction: a look at prosthetics--past, present and possible future.

作者信息

Mascarenhas Randy, MacDonald Peter B

机构信息

University of Pittsburgh Medical Center, Department of Orthopaedic Surgery, USA.

出版信息

Mcgill J Med. 2008 Jan;11(1):29-37.

Abstract

Biological tissue autograft reconstruction using the patellar tendon or quadrupled semitendinosus/gracilis tendons has become the most popular procedure in surgical treatment of a ruptured ACL. This article provides a review of the history of the use of prosthetics with respect to ACL reconstruction grafts including Carbon Fibre, Gore-Tex and Dacron prosthetics as well as the Leeds-Keio Artificial Ligament and the Kennedy Ligament Augmentation Device (LAD). Emphasis is placed on the Ligament Advanced Reinforcement System (LARS) as preliminary investigations of its use have been encouraging. Significant progress has been made recently with respect to the understanding of ACL anatomy, composition, biomechanics, and healing processes, leading to innovative techniques using approaches based in tissue engineering principles and computer - assisted surgery. While research into improved ACL treatment options continues, the synthesis of recent advancements provides a new optimism towards the regeneration of an ACL mirroring its original stability, function, and longevity.

摘要

使用髌腱或四股半腱肌/股薄肌腱进行生物组织自体移植重建已成为外科治疗前交叉韧带(ACL)断裂最常用的方法。本文回顾了在ACL重建移植物中使用假体的历史,包括碳纤维、戈尔特斯(Gore-Tex)和涤纶假体,以及利兹-庆应人工韧带和肯尼迪韧带增强装置(LAD)。重点介绍了韧带高级强化系统(LARS),因为对其使用的初步研究令人鼓舞。最近在对ACL的解剖结构、组成、生物力学和愈合过程的理解方面取得了重大进展,从而产生了基于组织工程原理和计算机辅助手术方法的创新技术。虽然对改进的ACL治疗方案的研究仍在继续,但近期进展的综合成果为重建出具有原始稳定性、功能和寿命的ACL带来了新的乐观态度。

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