Thalasselis A, Selim A A
Vision Institute, Buenos Aires, Argentina.
Optom Vis Sci. 1991 May;68(5):357-63. doi: 10.1097/00006324-199105000-00006.
This report describes the unusual case of 46-year-old white European woman who presented spontaneous keratoconus. This case suggests a new association: keratoconus-tetany-menopause. This can be explained by Thalasselis' syndrome, a syndrome showing a relation between keratoconus, magnesium (Mg) deficiency, type A behavior, and allergy. Furthermore, Thalasselis' syndrome integrates old and new theories. This report also suggests that the alteration induced by severe but reversible Mg deficiency at the intra- and extracellular levels, associated with metabolic and hormonal imbalances, may trigger the development of keratoconus. Clinical data which support this thesis are reported.
本报告描述了一名46岁的欧洲白人女性出现自发性圆锥角膜的罕见病例。该病例提示了一种新的关联：圆锥角膜-手足搐搦-更年期。这可以用塔拉萨利斯综合征来解释，该综合征显示了圆锥角膜、镁（Mg）缺乏、A型行为和过敏之间的关系。此外，塔拉萨利斯综合征整合了新旧理论。本报告还表明，严重但可逆的镁缺乏在细胞内和细胞外水平引起的改变，与代谢和激素失衡相关，可能触发圆锥角膜的发展。报告了支持这一论点的临床数据。
