Suppr超能文献

神经元干细胞中的转化生长因子-β信号传导

TGF-beta signaling in neuronal stem cells.

作者信息

Yun Chohee, Mendelson Jonathan, Blake Tiffany, Mishra Lopa, Mishra Bibhuti

机构信息

Laboratory of Developmental Neurobiology, Department of Surgery, Medicine & Lombardi Cancer Center, Georgetown University, Washington, DC 20007, USA.

出版信息

Dis Markers. 2008;24(4-5):251-5. doi: 10.1155/2008/747343.

DOI:10.1155/2008/747343
PMID:18525119
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3850609/
Abstract

Transforming growth factor beta (TGF-beta) signaling has diverse and complex roles in various biological phenomena such as cell growth, differentiation, embryogenesis and morphogenesis. ES cells provide an essential model for understanding the role of TGF-beta signaling in lineage specification and differentiation. Recent studies have suggested significant role of TGF-beta in stem/progenitor cell biology. Here in this review, we focus on the role of the TGF-beta superfamily in neuronal development.

摘要

转化生长因子β（TGF-β）信号通路在细胞生长、分化、胚胎发生和形态发生等各种生物学现象中具有多样而复杂的作用。胚胎干细胞为理解TGF-β信号通路在细胞谱系特化和分化中的作用提供了重要模型。最近的研究表明TGF-β在干/祖细胞生物学中具有重要作用。在本综述中，我们聚焦于TGF-β超家族在神经元发育中的作用。

相似文献

1
TGF-beta signaling in neuronal stem cells.神经元干细胞中的转化生长因子-β信号传导
Dis Markers. 2008;24(4-5):251-5. doi: 10.1155/2008/747343.
2
Transforming growth factor-beta signaling in stem cells and cancer.干细胞与癌症中的转化生长因子-β信号传导
Science. 2005 Oct 7;310(5745):68-71. doi: 10.1126/science.1118389.
3
TGF-beta, neuronal stem cells and glioblastoma.转化生长因子-β、神经干细胞与胶质母细胞瘤
Oncogene. 2005 Aug 29;24(37):5722-30. doi: 10.1038/sj.onc.1208925.
4
TGF-β Signaling in Stem Cell Regulation.转化生长因子-β信号通路在干细胞调控中的作用
Methods Mol Biol. 2016;1344:137-45. doi: 10.1007/978-1-4939-2966-5_8.
5
Transforming growth factor-beta and notch signaling mediate stem cell differentiation into smooth muscle cells.转化生长因子-β和 Notch 信号通路介导干细胞向平滑肌细胞分化。
Stem Cells. 2010 Apr;28(4):734-42. doi: 10.1002/stem.319.
6
Dynamic regulation of Notch signaling in neural progenitor cells.神经祖细胞中 Notch 信号的动态调控。
Curr Opin Cell Biol. 2009 Dec;21(6):733-40. doi: 10.1016/j.ceb.2009.08.009. Epub 2009 Sep 23.
7
Tgf-Beta signaling in development.发育过程中的转化生长因子-β信号传导
Sci STKE. 2007 Aug 14;2007(399):cm1. doi: 10.1126/stke.3992007cm1.
8
Turning it up a Notch: cross-talk between TGF beta and Notch signaling.进一步提升：转化生长因子β与Notch信号通路之间的相互作用
Bioessays. 2005 Feb;27(2):115-8. doi: 10.1002/bies.20187.
9
Transforming growth factor beta is required for differentiation of mouse mesencephalic progenitors into dopaminergic neurons in vitro and in vivo: ectopic induction in dorsal mesencephalon.转化生长因子β是小鼠中脑祖细胞在体外和体内分化为多巴胺能神经元所必需的：在中脑背侧的异位诱导
Stem Cells. 2006 Sep;24(9):2120-9. doi: 10.1634/stemcells.2005-0514. Epub 2006 Jun 1.
10
The transforming growth factor-betas: structure, signaling, and roles in nervous system development and functions.转化生长因子-β：结构、信号传导及其在神经系统发育和功能中的作用
J Neurochem. 2000 Dec;75(6):2227-40. doi: 10.1046/j.1471-4159.2000.0752227.x.

引用本文的文献

1
Growth factors-based beneficial effects of platelet lysate on umbilical cord-derived stem cells and their synergistic use in osteoarthritis treatment.基于生长因子的血小板裂解液对脐带间充质干细胞的有益作用及其在骨关节炎治疗中的协同应用。
Cell Death Dis. 2020 Oct 14;11(10):857. doi: 10.1038/s41419-020-03045-0.
2
MicroRNA Profiling During Neural Differentiation of Induced Pluripotent Stem Cells.诱导多能干细胞神经分化过程中的 microRNA 谱分析。
Int J Mol Sci. 2019 Jul 26;20(15):3651. doi: 10.3390/ijms20153651.
3
Fetal Cerebrovascular Maturation: Effects of Hypoxia.胎儿脑血管成熟：缺氧的影响。
Semin Pediatr Neurol. 2018 Dec;28:17-28. doi: 10.1016/j.spen.2018.05.003. Epub 2018 Jun 20.
4
Gestational Hypoxia and Developmental Plasticity.妊娠期缺氧与发育可塑性。
Physiol Rev. 2018 Jul 1;98(3):1241-1334. doi: 10.1152/physrev.00043.2017.
5
Cerium oxide nanoparticles inhibit differentiation of neural stem cells.氧化铈纳米颗粒抑制神经干细胞的分化。
Sci Rep. 2017 Aug 24;7(1):9284. doi: 10.1038/s41598-017-09430-8.
6
Self-regulatory factors of embryonic stem cells in co-culture with stromal cells enhance neural differentiation.与基质细胞共培养时胚胎干细胞的自我调节因子可增强神经分化。
Integr Biol (Camb). 2017 May 22;9(5):418-426. doi: 10.1039/c7ib00038c.
7
Network of brain protein level changes in glutaminase deficient fetal mice.谷氨酸酶缺乏型胎鼠脑内蛋白水平变化网络。
J Proteomics. 2013 Mar 27;80:236-49. doi: 10.1016/j.jprot.2013.01.013. Epub 2013 Jan 30.
8
TGFβ signaling induces expression of Gadd45b in retinal ganglion cells.TGFβ 信号诱导视网膜神经节细胞中 Gadd45b 的表达。
Invest Ophthalmol Vis Sci. 2013 Feb 5;54(2):1061-9. doi: 10.1167/iovs.12-10142.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验