DiLaura Robert, Turisco Fran, McGrew Cherri, Reel Stephanie, Glaser John, Crowley William F
Cleveland Clinic and Case Western Reserve University, Lerner Research Institute, Cleveland, OH, USA.
J Investig Med. 2008 Jun;56(5):770-9. doi: 10.2310/JIM.0b013e3175d7b4.
Data on the state of information systems infrastructures used in the clinical research enterprise of academic medical centers are limited and mostly anecdotal. What has been published is slowly beginning to make important distinctions, such as clinical trials as a specialized form of clinical research and between "Informatics" in an academic setting from health care information technology. However, this field continues to undergo fundamental changes, accelerated by the National Institutes of Health's creation of Clinical and Translational Science Awards to build a new "home" for biomedical research.
We surveyed all Clinical Research Forum member institutions regarding their enterprise infrastructure and use of information systems in support of clinical research. The questions in this on-line study expanded on one first done in 2005. Of the 52 sites invited, 19 (37%) responded. We analyzed the responses and also made matched comparisons for those organizations that participated in both surveys.
Although there continues to be conceptual agreement on information system elements for the clinical research enterprise, no single institution achieved the ideal, a similar result to the 2005 survey. Indeed, little progress was made over the past 2 years at most locations other than in information technology planning, strategy, and governance.
There is increased recognition of the importance of information systems infrastructure and expertise for biomedical research, but the needs are accelerating much faster than institutions can build or pay for. A much greater realization of and innovative solution for this growing chasm is urgently required.
关于学术医疗中心临床研究机构所使用的信息系统基础设施状况的数据有限，且大多为轶事性描述。已发表的内容正逐渐开始做出重要区分，例如将临床试验作为临床研究的一种特殊形式，以及区分学术环境中的“信息学”与医疗保健信息技术。然而，该领域仍在经历根本性变革，美国国立卫生研究院设立临床与转化科学奖以构建生物医学研究的新“家园”，加速了这一变革。
我们就其企业基础设施以及支持临床研究的信息系统使用情况，对所有临床研究论坛成员机构进行了调查。本次在线研究中的问题在2005年首次开展的一项研究基础上进行了扩展。在受邀的52个机构中，19个（37%）做出了回应。我们分析了这些回复，并对参与了两项调查的机构进行了匹配比较。
尽管对于临床研究机构的信息系统要素仍存在概念上的共识，但没有一家机构达到理想状态，这与2005年的调查结果类似。事实上，在过去两年里，除了信息技术规划、战略和治理方面，大多数机构进展甚微。
人们越来越认识到信息系统基础设施和专业知识对生物医学研究的重要性，但需求增长的速度远远超过机构的建设或支付能力。迫切需要对这一日益扩大的差距有更深刻的认识并找到创新解决方案。
