Ha Kee-Yong, Na Ki-Ho, Shin Jae-Hyuk, Kim Ki-Won
Department of Orthopaedic Surgery, Kang-Nam St Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul.
J Spinal Disord Tech. 2008 Jun;21(4):229-34. doi: 10.1097/BSD.0b013e3180eaa202.
The surgical approach that should be used for degenerative spondylolisthesis (DS) is a controversial issue. Decompression and posterolateral fusion (PLF) with or without lumbar interbody fusion is widely used. Many studies have compared the outcomes of these 2 approaches, but the appropriate indications for these approaches are still unclear. The authors retrospectively studied the effects of posterior lumbar interbody fusion (PLIF) after PLF for the treatment of DS.
Forty patients who underwent single level decompression and posterior instrumentation for DS at L4-5 and were followed for at least 2 years were retrospectively studied. The patients were divided into 4 groups: the stable PLF group (S-PLF, n=13); the stable PLF with additional PLIF group (S-PLIF, n=11); the unstable PLF group (U-PLF, n=8); and the unstable PLF with additional PLIF group (U-PLIF, n=8). Clinical and radiographic comparisons were carried out between the S-PLF and S-PLIF groups, and between the U-PLF and U-PLIF groups.
Clinical assessments, using the improvements of the Oswestry Disability Index (ODI) and the Visual Analog Scale (VAS), were statistically significantly different between the 2 unstable groups (DeltaU-PLF <DeltaU-PLIF, P(ODI)=0.032, P(VAS)=0.004, respectively). On radiologic assessment, the slip angle increment was significantly different between the 2 stable groups (DeltaS-PLF>DeltaS-PLIF, P=0.029), and the disc height increment was significantly different between the 2 stable groups (DeltaS-PLF<DeltaS-PLIF, P=0.043) and between the 2 unstable groups (DeltaU-PLF<DeltaU-PLIF, P=0.042).
This study suggests that preoperative segmental instability may be a criterion determining whether an additional PLIF would be beneficial in the treatment of lumbar DS.
用于退行性腰椎滑脱症(DS)的手术方式是一个存在争议的问题。减压及后外侧融合术(PLF),无论是否联合腰椎椎间融合术,都被广泛应用。许多研究比较了这两种手术方式的疗效,但这两种手术方式的合适适应证仍不明确。作者回顾性研究了PLF术后行后路腰椎椎间融合术(PLIF)治疗DS的效果。
回顾性研究40例因L4-5节段DS接受单节段减压及后路内固定且随访至少2年的患者。患者被分为4组:稳定PLF组(S-PLF,n = 13);稳定PLF联合额外PLIF组(S-PLIF,n = 11);不稳定PLF组(U-PLF,n = 8);不稳定PLF联合额外PLIF组(U-PLIF,n = 8)。对S-PLF组和S-PLIF组之间以及U-PLF组和U-PLIF组之间进行临床和影像学比较。
使用Oswestry功能障碍指数(ODI)和视觉模拟量表(VAS)改善情况进行的临床评估显示,两个不稳定组之间存在统计学显著差异(ΔU-PLF < ΔU-PLIF,P(ODI)=0.032,P(VAS)=0.004)。在影像学评估中,两个稳定组之间的滑脱角增量存在显著差异(ΔS-PLF > ΔS-PLIF,P = 0.029),两个稳定组之间以及两个不稳定组之间的椎间盘高度增量存在显著差异(ΔS-PLF < ΔS-PLIF,P = 0.043;ΔU-PLF < ΔU-PLIF,P = 0.042)。
本研究表明术前节段性不稳定可能是决定额外PLIF治疗腰椎DS是否有益的一个标准。