紫背橐吾中的呋喃埃瑞莫菲烷类化合物。

Furanoeremophilanes from Ligularia atroviolacea.

作者信息

Shi Shu-Yun, Zhao Yu, Zhang Yu-Ping, Huang Ke-Long

机构信息

School of Chemistry and Chemical Engineering, Central South University, Changsha 410083, People's Republic of China.

出版信息

Fitoterapia. 2008 Sep;79(6):476-8. doi: 10.1016/j.fitote.2008.02.012. Epub 2008 Jun 5.

DOI:10.1016/j.fitote.2008.02.012

PMID:18534775

Abstract

A new furanoeremophilane, 1alpha-chloro-6beta-isobutyroxy-9-oxo-10beta-hydroxy-furanoeremophilane (1) was isolated from the root of Ligularia atroviolacea and identified mainly on the basis of detailed spectral analyses including X-ray. Moreover, five known furanoeremophilanes,1alpha-hydroxy-6beta-isobutyroxy-9-oxo-10beta-H-furanoeremophilane (2), 1alpha-hydroxy-6beta-isobutyroxy-9-oxo-10alpha-H-furanoeremophilane (3), 1alpha,10beta-dihydroxy-6beta-angeloyloxy-9-oxo-furanoeremophilane (4), furanoeremophil-3-en-15,6alpha-olide (5) and furanoeremophil-15beta,6alpha-olide (6) were isolated from the same source.

摘要

从紫背橐吾的根中分离得到一种新的呋喃雅槛蓝烷，1α-氯-6β-异丁酰氧基-9-氧代-10β-羟基-呋喃雅槛蓝烷（1），主要通过包括X射线在内的详细光谱分析进行鉴定。此外，还从同一来源分离出了五种已知的呋喃雅槛蓝烷，1α-羟基-6β-异丁酰氧基-9-氧代-10β-H-呋喃雅槛蓝烷（2）、1α-羟基-6β-异丁酰氧基-9-氧代-10α-H-呋喃雅槛蓝烷（3）、1α,10β-二羟基-6β-当归酰氧基-9-氧代-呋喃雅槛蓝烷（4）、呋喃雅槛蓝-3-烯-15,6α-内酯（5）和呋喃雅槛蓝-15β,6α-内酯（6）。