在C端脯氨酸残基处标记的三肽脯氨酸-甘氨酸-脯氨酸与大鼠前脑质膜的结合。 - Suppr

Binding of tripeptide Pro-Gly-Pro labeled at the C-terminal proline residue to plasma membranes of the rat forebrain.

作者信息

V'unova T V, Andreeva L A, Shevchenko K V, Shevchenko V P, Bobrov M Yu, Bezuglov V V, Myasoedov N F

机构信息

Institute of Molecular Genetics, Russian Academy of Sciences, pl. Akademika Kurchatova 46, D-182, Moscow, 123182, Russia.

出版信息

Dokl Biol Sci. 2008 Mar-Apr;419:95-6. doi: 10.1134/s0012496608020075.

DOI:10.1134/s0012496608020075

PMID:18536271

Abstract

摘要

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Binding of tripeptide Pro-Gly-Pro labeled at the C-terminal proline residue to plasma membranes of the rat forebrain.在C端脯氨酸残基处标记的三肽脯氨酸-甘氨酸-脯氨酸与大鼠前脑质膜的结合。

Dokl Biol Sci. 2008 Mar-Apr;419:95-6. doi: 10.1134/s0012496608020075.

Characteristic features of specific binding of pentapeptide HFPGP labeled at the C-terminal proline residue to rat forebrain plasma membranes.

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The peptide-substrate-binding domain of human collagen prolyl 4-hydroxylases. Backbone assignments, secondary structure, and binding of proline-rich peptides.人胶原蛋白脯氨酰 4-羟化酶的肽底物结合结构域。主链归属、二级结构以及富含脯氨酸肽的结合

J Biol Chem. 2003 Sep 12;278(37):34966-74. doi: 10.1074/jbc.M303624200. Epub 2003 Jun 24.

Transport of L-proline, L-proline-containing peptides and related drugs at mammalian epithelial cell membranes.

Amino Acids. 2006 Sep;31(2):119-36. doi: 10.1007/s00726-006-0307-0. Epub 2006 Apr 20.

Interaction of prolyl 4-hydroxylase with synthetic peptide substrates. A conformational model for collagen proline hydroxylation.脯氨酰4-羟化酶与合成肽底物的相互作用。胶原蛋白脯氨酸羟化的构象模型。

J Biol Chem. 1991 Feb 15;266(5):2852-8.

The amino acid sequence of a salivary proline-rich peptide, P-C, and its relation to a salivary proline-rich phosphoprotein, protein C.一种富含脯氨酸的唾液肽P-C的氨基酸序列及其与一种富含脯氨酸的唾液磷蛋白C蛋白的关系。

J Biochem. 1980 Apr;87(4):1071-7.

Structure and activity of angiotensin I converting enzyme inhibitory peptides derived from Alaskan pollack skin.源自阿拉斯加狭鳕鱼皮的血管紧张素I转换酶抑制肽的结构与活性

J Biochem Mol Biol. 2002 Mar 31;35(2):239-43. doi: 10.5483/bmbrep.2002.35.2.239.

Evidence for 4-hydroxyproline in viral proteins. Characterization of a viral prolyl 4-hydroxylase and its peptide substrates.病毒蛋白中4-羟基脯氨酸的证据。一种病毒脯氨酰4-羟化酶及其肽底物的特性。

J Biol Chem. 1999 Aug 6;274(32):22131-4. doi: 10.1074/jbc.274.32.22131.

Phosphoproteins in the parotid saliva from the subhuman primate Macaca fascicularis. Isolation and characterization of a proline-rich phosphoglycoprotein and the complete covalent structure of a proline-rich phosphopeptide.来自猕猴（食蟹猴）腮腺唾液中的磷蛋白。富含脯氨酸的磷酸糖蛋白的分离与特性鉴定以及富含脯氨酸的磷酸肽的完整共价结构。

J Biol Chem. 1982 Aug 25;257(16):9271-82.

[The binding of Semax, ACTH 4-10 heptapeptide, to plasma membranes of the rat forebrain basal nuclei and its biodegradation].

Bioorg Khim. 2004 May-Jun;30(3):241-6. doi: 10.1023/b:rubi.0000030127.46845.f0.

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Regulatory Peptide Pro-Gly-Pro Accelerates Neuroregeneration of Primary Neuroglial Culture after Mechanical Injury in Scratch Test.调节肽 Pro-Gly-Pro 促进划痕试验机械损伤后原代神经胶质培养的神经再生。

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Genes (Basel). 2023 Jun 30;14(7):1382. doi: 10.3390/genes14071382.

Insight into Glyproline Peptides' Activity through the Modulation of the Inflammatory and Neurosignaling Genetic Response Following Cerebral Ischemia-Reperfusion.通过调节脑缺血再灌注后炎症和神经信号遗传反应来深入了解甘氨酰脯氨酸肽的活性。

Genes (Basel). 2022 Dec 16;13(12):2380. doi: 10.3390/genes13122380.

Characteristic features of specific binding of pentapeptide HFPGP labeled at the C-terminal proline residue to rat forebrain plasma membranes.

Dokl Biochem Biophys. 2014 May;456(1):101-3. doi: 10.1134/S1607672914030077. Epub 2014 Jul 4.

本文引用的文献

[Evenly tritium-labeled peptides and their in vivo and in vitro biodegradation].[均匀氚标记肽及其体内和体外生物降解]

Bioorg Khim. 2006 Mar-Apr;32(2):183-91.

[Kinetics of Semax penetration into the brain and blood of rats after its intranasal administration].[鼻腔给药后赛美克斯在大鼠脑和血液中的渗透动力学]

Bioorg Khim. 2006 Jan-Feb;32(1):64-70. doi: 10.1134/s1068162006010055.

C-terminal Pro-Gly-Pro tripeptide in contrast to full-length neuropeptide semax exhibits no neuroprotective effect in experimental cerebral ischemia.与全长神经肽司美格鲁肽相比，C末端脯氨酰-甘氨酰-脯氨酸三肽在实验性脑缺血中无神经保护作用。

Bull Exp Biol Med. 2005 Apr;139(4):421-3. doi: 10.1007/s10517-005-0311-5.

Natural and hybrid ("chimeric") stable regulatory glyproline peptides.天然及杂合（“嵌合”）稳定调节性甘脯肽。

Pathophysiology. 2005 May;11(4):179-185. doi: 10.1016/j.pathophys.2004.10.001.

Effect of peptide Pro-Gly-Pro on stress-induced behavioral changes in rats.肽Pro-Gly-Pro对大鼠应激诱导行为变化的影响。

Bull Exp Biol Med. 2004 Jul;138(1):5-7. doi: 10.1023/b:bebm.0000046923.37415.4e.

Secretory activity of mast cell during stress: effect of prolyl-glycyl-proline and Semax.应激期间肥大细胞的分泌活性：脯氨酰-甘氨酰-脯氨酸和赛美克斯的作用

Bull Exp Biol Med. 2003 Oct;136(4):325-7. doi: 10.1023/b:bebm.0000010942.14275.50.

[Semax and some glyproline peptides accelerate the healing of acetic ulcers in rats].

Eksp Klin Gastroenterol. 2003(4):88-92, 117.

Comparative study of modulatory effects of Semax and primary proline-containing peptides on hemostatic reactions.Semax与含脯氨酸的初级肽对止血反应调节作用的比较研究。

Bull Exp Biol Med. 2001 Jul;132(1):625-6. doi: 10.1023/a:1012503606536.

The simplest proline-containing peptides PG, GP, PGP, and GPGG: regulatory activity and possible sources of biosynthesis.最简单的含脯氨酸肽PG、GP、PGP和GPGG：调节活性及可能的生物合成来源。

Biochemistry (Mosc). 1998 Feb;63(2):119-24.

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Binding of tripeptide Pro-Gly-Pro labeled at the C-terminal proline residue to plasma membranes of the rat forebrain.

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