Kon Yoko, Iida Tomohiro, Maruko Ichiro, Saito Masaaki
Department of Ophthalmology, Fukushima Medical University School of Medicine, Fukushima, Japan.
Retina. 2008 Jun;28(6):864-9. doi: 10.1097/IAE.0b013e3181669795.
To report the exact location of multiple yellowish dot-like precipitates in central serous chorioretinopathy (CSC) with the Optical Coherence Tomography (OCT)-Ophthalmoscope (Nidek-OTI, Gamagori, Japan).
Retrospective, observational study.
Twenty eyes of 18 patients (average age, 53 years) with CSC were examined by the OCT-Ophthalmoscope. Multiple yellowish dot-like precipitates were seen in all eyes by biomicroscopic examination.
Multiple highly reflective dots (bright dots) were seen by the OCT-Ophthalmoscope in all 20 eyes. The bright dots were observed on the posterior surface of the detached neurosensory retina by cross-sectional B-scan OCT in all eyes and in the detached neurosensory retina in 14 eyes. The bright dots were preferentially located in the outer retinal layer. Transverse C-scan OCT confirmed that the location of the bright dots coincided with that of the precipitates.
Both cross-sectional B-scan and transverse C-scan images obtained with the OCT-Ophthalmoscope showed subretinal and intraretinal bright dots in eyes with CSC, which may indicate that the yellowish dot-like precipitates are not only on the posterior surface of the detached retina but also in the detached neurosensory retina. Intraretinal precipitates in eyes with CSC may result from the accumulation of proteins or macrophages with the phagocytized photoreceptor outer segments.
使用光学相干断层扫描 - 检眼镜(日本镰仓尼德克公司的Nidek - OTI)报告中心性浆液性脉络膜视网膜病变(CSC)中多个淡黄色点状沉淀物的确切位置。
回顾性观察研究。
对18例(平均年龄53岁)CSC患者的20只眼进行了光学相干断层扫描 - 检眼镜检查。通过生物显微镜检查,在所有眼中均可见多个淡黄色点状沉淀物。
光学相干断层扫描 - 检眼镜在所有20只眼中均可见多个高反射点(亮点)。在所有眼中,通过横断面B扫描光学相干断层扫描在脱离的神经感觉视网膜后表面观察到亮点,在14只眼中在脱离的神经感觉视网膜中观察到亮点。亮点优先位于视网膜外层。横向C扫描光学相干断层扫描证实亮点的位置与沉淀物的位置一致。
使用光学相干断层扫描 - 检眼镜获得的横断面B扫描和横向C扫描图像均显示CSC患者眼中视网膜下和视网膜内的亮点,这可能表明淡黄色点状沉淀物不仅位于脱离视网膜的后表面,也位于脱离的神经感觉视网膜内。CSC患者眼中视网膜内沉淀物可能是由于蛋白质或吞噬了光感受器外段的巨噬细胞的积聚所致。