由重组人肠道病毒B型变种引起的致命性新生儿心肌炎。
Fatal neonatal myocarditis caused by a recombinant human enterovirus-B variant.
作者信息
Krogstad Paul, Hammon Rebecca, Halnon Nancy, Whitton J Lindsay
机构信息
Department of Pediatrics, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.
出版信息
Pediatr Infect Dis J. 2008 Jul;27(7):668-9. doi: 10.1097/INF.0b013e31816b5d2a.
PMID:18536618
Abstract
We report a case of fatal myocarditis in a newborn infant who was infected with a human enterovirus detected by throat culture and RT-PCR for viral RNA in plasma. Whole genome sequence analysis revealed the virus to be a genomic chimera that likely arose from recombination between coxsackievirus B3 and two recently identified enteroviruses, EV 86 and EV97.
摘要
我们报告了一例新生儿致命性心肌炎病例，该新生儿感染了一种人类肠道病毒，通过咽喉培养及血浆中病毒RNA的逆转录聚合酶链反应（RT-PCR）检测到该病毒。全基因组序列分析显示，该病毒是一种基因组嵌合体，可能源于柯萨奇病毒B3与最近鉴定出的两种肠道病毒EV 86和EV97之间的重组。
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