Kai K, Ikeda H, Yuasa Y, Suzuki S, Odaka T
J Virol. 1976 Nov;20(2):436-40. doi: 10.1128/JVI.20.2.436-440.1976.
Mouse strain G was studied for its susceptibility to various strains of murine leukemia and sarcoma viruses. Both N- and NB-tropic Friend leukemia viruses neither induced splenomegaly nor grew efficiently in strain G mice. Using the XC test, cultured embryo cells were found to be resistant, but not absolutely, to all the tested viruses, N-tropic AKR virus, N- and NB-tropic Friend leukemia viruses, NB-tropic Rauscher leukemia virus, B-tropic WN1802B virus, NB-tropic Moloney leukemia and sarcoma viruses, and N-tropic Kirsten sarcoma virus, although the resistance to Moloney leukemia and sarcoma viruses is sometimes not as strong as that for other viruses. Thus, the strain G mice are unique among mouse strains because they show resistance that is not related to the N-B tropism of murine leukemia viruses.
对小鼠品系G对各种鼠白血病和肉瘤病毒的易感性进行了研究。N嗜性和NB嗜性的弗氏白血病病毒既不引起脾肿大,在品系G小鼠中也不能有效生长。通过XC试验发现,培养的胚胎细胞对所有测试病毒,即N嗜性AKR病毒、N嗜性和NB嗜性弗氏白血病病毒、NB嗜性劳氏白血病病毒、B嗜性WN1802B病毒、NB嗜性莫洛尼白血病和肉瘤病毒以及N嗜性柯斯顿肉瘤病毒具有抗性,但并非绝对抗性,尽管对莫洛尼白血病和肉瘤病毒的抗性有时不如对其他病毒的抗性强。因此,品系G小鼠在小鼠品系中是独特的,因为它们表现出的抗性与鼠白血病病毒的N-B嗜性无关。