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对N-、B-和NB嗜性鼠白血病病毒具有抗性的小鼠品系。

Mouse strain resistant to N-, B-, and NB-tropic murine leukemia viruses.

作者信息

Kai K, Ikeda H, Yuasa Y, Suzuki S, Odaka T

出版信息

J Virol. 1976 Nov;20(2):436-40. doi: 10.1128/JVI.20.2.436-440.1976.

DOI:10.1128/JVI.20.2.436-440.1976
PMID:185426
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC355011/
Abstract

Mouse strain G was studied for its susceptibility to various strains of murine leukemia and sarcoma viruses. Both N- and NB-tropic Friend leukemia viruses neither induced splenomegaly nor grew efficiently in strain G mice. Using the XC test, cultured embryo cells were found to be resistant, but not absolutely, to all the tested viruses, N-tropic AKR virus, N- and NB-tropic Friend leukemia viruses, NB-tropic Rauscher leukemia virus, B-tropic WN1802B virus, NB-tropic Moloney leukemia and sarcoma viruses, and N-tropic Kirsten sarcoma virus, although the resistance to Moloney leukemia and sarcoma viruses is sometimes not as strong as that for other viruses. Thus, the strain G mice are unique among mouse strains because they show resistance that is not related to the N-B tropism of murine leukemia viruses.

摘要

对小鼠品系G对各种鼠白血病和肉瘤病毒的易感性进行了研究。N嗜性和NB嗜性的弗氏白血病病毒既不引起脾肿大,在品系G小鼠中也不能有效生长。通过XC试验发现,培养的胚胎细胞对所有测试病毒,即N嗜性AKR病毒、N嗜性和NB嗜性弗氏白血病病毒、NB嗜性劳氏白血病病毒、B嗜性WN1802B病毒、NB嗜性莫洛尼白血病和肉瘤病毒以及N嗜性柯斯顿肉瘤病毒具有抗性,但并非绝对抗性,尽管对莫洛尼白血病和肉瘤病毒的抗性有时不如对其他病毒的抗性强。因此,品系G小鼠在小鼠品系中是独特的,因为它们表现出的抗性与鼠白血病病毒的N-B嗜性无关。

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本文引用的文献

1
Inheritance of susceptibility to Friend mouse leukemia virus.对弗瑞德小鼠白血病病毒易感性的遗传
Jpn J Exp Med. 1962 Oct;32:405-13.
2
Cell-free transmission in adult Swiss mice of a disease having the character of a leukemia.具有白血病特征的疾病在成年瑞士小鼠中的无细胞传播。
J Exp Med. 1957 Apr 1;105(4):307-18. doi: 10.1084/jem.105.4.307.
3
Requirement of cellular DNA synthesis for the growth of Friend leukemia virus.弗瑞德白血病病毒生长对细胞DNA合成的需求
Exp Cell Res. 1968 Oct;52(2):445-50. doi: 10.1016/0014-4827(68)90486-2.
4
Fv-2: identification and location of a second gene governing the spleen focus response to Friend leukemia virus in mice.Fv-2:小鼠中控制对Friend白血病病毒的脾集落反应的第二个基因的鉴定与定位
J Natl Cancer Inst. 1970 Jul;45(1):163-9.
5
Rapid cell culture assay technic for murine leukaemia viruses.鼠白血病病毒的快速细胞培养测定技术
Nature. 1971 Feb 19;229(5286):564-6. doi: 10.1038/229564b0.
6
Inheritance of susceptibility to Friend mouse leukemia virus. XII. Effects of the Fv-1 locus.对Friend小鼠白血病病毒易感性的遗传。十二。Fv-1基因座的作用。
Int J Cancer. 1974 Aug 15;14(2):252-8. doi: 10.1002/ijc.2910140214.
7
Cell culture from a rat brain tumor induced by intracerebral inoculation with murine sarcoma virus.通过脑内接种鼠肉瘤病毒诱导的大鼠脑肿瘤的细胞培养。
J Natl Cancer Inst. 1974 Aug;53(2):431-47. doi: 10.1093/jnci/53.2.431.
8
Inheritance of susceptibility to Friend mouse leukemia virus. X. Separate genetic control of two viruses in Friend virus preparation.对Friend小鼠白血病病毒易感性的遗传。X. Friend病毒制剂中两种病毒的独立遗传控制。
Int J Cancer. 1973 May;11(3):567-74. doi: 10.1002/ijc.2910110308.
9
Studies of genetic transmission of murine leukemia virus by AKR mice. II. Crosses with Fv-1 b strains of mice.AKR小鼠对鼠白血病病毒的遗传传递研究。II. 与Fv-1 b系小鼠的杂交
J Exp Med. 1972 Nov 1;136(5):1286-301. doi: 10.1084/jem.136.5.1286.
10
Isolation and characterization of a lymphatic leukemia virus in the Friend virus complex.从弗氏病毒复合体中分离并鉴定一种淋巴白血病病毒。
J Natl Cancer Inst. 1971 Jun;46(6):1209-17.