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相似文献

1
Murine retroviral restriction genes Fv-4 and Akvr-1 are alleles of a single locus.小鼠逆转录病毒限制基因Fv-4和Akvr-1是单个基因座的等位基因。
J Virol. 1983 Sep;47(3):649-51. doi: 10.1128/JVI.47.3.649-651.1983.
2
Akvr-1, a dominant murine leukemia virus restriction gene, is polymorphic in leukemia-prone wild mice.Akvr-1是一种显性鼠白血病病毒限制基因，在易患白血病的野生小鼠中具有多态性。
Proc Natl Acad Sci U S A. 1980 Jan;77(1):531-5. doi: 10.1073/pnas.77.1.531.
3
Molecular characterization of the Akvr-1 restriction gene: a defective endogenous retrovirus-borne gene identical to Fv-4r.Akvr-1限制基因的分子特征：一个与Fv-4r相同的有缺陷的内源性逆转录病毒携带基因。
J Virol. 1987 Feb;61(2):308-14. doi: 10.1128/JVI.61.2.308-314.1987.
4
Resistance to fibroblasts and hematopoietic cells to ecotropic murine leukemia virus infection; an Akvr-1R gene effect.成纤维细胞和造血细胞对嗜亲性鼠白血病病毒感染的抗性；一种Akvr-1R基因效应。
Int J Cancer. 1983 Apr 15;31(4):491-6. doi: 10.1002/ijc.2910310415.
5
Analysis of wild-derived mice for Fv-1 and Fv-2 murine leukemia virus restriction loci: a novel wild mouse Fv-1 allele responsible for lack of host range restriction.对野生来源小鼠的Fv-1和Fv-2鼠白血病病毒限制位点的分析：一种导致缺乏宿主范围限制的新型野生小鼠Fv-1等位基因。
J Virol. 1985 Aug;55(2):281-5. doi: 10.1128/JVI.55.2.281-285.1985.
6
Studies of genetic transmission of murine leukemia virus by AKR mice. I. Crosses with Fv-1 n strains of mice.AKR小鼠对鼠白血病病毒的遗传传递研究。I. 与Fv-1 n系小鼠的杂交。
J Exp Med. 1972 Nov 1;136(5):1272-85. doi: 10.1084/jem.136.5.1272.
7
Studies of genetic transmission of murine leukemia virus by AKR mice. II. Crosses with Fv-1 b strains of mice.AKR小鼠对鼠白血病病毒的遗传传递研究。II. 与Fv-1 b系小鼠的杂交
J Exp Med. 1972 Nov 1;136(5):1286-301. doi: 10.1084/jem.136.5.1286.
8
Relationship of infectious murine leukemia virus and virus-related antigens in genetic crosses between AKR and the Fv-1 compatible strain C57L.感染性鼠白血病病毒与病毒相关抗原在AKR和Fv-1相容品系C57L之间遗传杂交中的关系
J Exp Med. 1976 Jan 1;143(1):32-46. doi: 10.1084/jem.143.1.32.
9
Friend murine leukemia virus resistance in Japanese wild mice: possible allelism with Fv-4 in FRG mice.日本野生小鼠对Friend鼠白血病病毒的抗性：与FRG小鼠中Fv-4可能的等位性。
J Natl Cancer Inst. 1981 Apr;66(4):729-31.
10
Molecular mechanism of an ecotropic MuLV restriction gene Akvr-1/FV-4 in California wild mice.
Curr Top Microbiol Immunol. 1986;127:338-45. doi: 10.1007/978-3-642-71304-0_41.

引用本文的文献

1
Switching Sides: How Endogenous Retroviruses Protect Us from Viral Infections.转换立场：内源性逆转录病毒如何保护我们免受病毒感染。
J Virol. 2021 May 24;95(12). doi: 10.1128/JVI.02299-20.
2
Insights into mammalian biology from the wild house mouse Mus musculus.从野生家鼠小家鼠洞察哺乳动物生物学。
Elife. 2015 Apr 15;4:e05959. doi: 10.7554/eLife.05959.
3
Identification of ejaculated proteins in the house mouse (Mus domesticus) via isotopic labeling.通过同位素标记鉴定家鼠（Mus domesticus）的射出蛋白。
BMC Genomics. 2011 Jun 10;12:306. doi: 10.1186/1471-2164-12-306.
4
Transgenic Fv-4 mice resistant to Friend virus.对Friend病毒有抗性的转基因Fv-4小鼠。
J Virol. 1993 Jul;67(7):4163-8. doi: 10.1128/JVI.67.7.4163-4168.1993.
5
Genetic control of retroviral disease in aging wild mice.衰老野生小鼠逆转录病毒疾病的遗传控制
Genetica. 1993;91(1-3):199-209. doi: 10.1007/BF01435998.
6
A unique sequence related to the ecotropic murine leukemia virus is associated with the Fv-4 resistance gene.与亲嗜性鼠白血病病毒相关的一个独特序列与Fv-4抗性基因有关。
Proc Natl Acad Sci U S A. 1984 Feb;81(3):834-7. doi: 10.1073/pnas.81.3.834.
7
Diverse wild mouse origins of xenotropic, mink cell focus-forming, and two types of ecotropic proviral genes.嗜异性、貂细胞集落形成及两种亲嗜性前病毒基因的多种野生小鼠起源
J Virol. 1987 Oct;61(10):3082-8. doi: 10.1128/JVI.61.10.3082-3088.1987.
8
Molecular characterization of the Akvr-1 restriction gene: a defective endogenous retrovirus-borne gene identical to Fv-4r.Akvr-1限制基因的分子特征：一个与Fv-4r相同的有缺陷的内源性逆转录病毒携带基因。
J Virol. 1987 Feb;61(2):308-14. doi: 10.1128/JVI.61.2.308-314.1987.
9
Characterization of a molecularly cloned retroviral sequence associated with Fv-4 resistance.与Fv-4抗性相关的分子克隆逆转录病毒序列的特性分析
J Virol. 1985 Sep;55(3):768-77. doi: 10.1128/JVI.55.3.768-777.1985.
10
Fv-4 resistance gene: a truncated endogenous murine leukemia virus with ecotropic interference properties.Fv-4抗性基因：一种具有嗜亲性干扰特性的截短型内源性鼠白血病病毒。
J Virol. 1989 Dec;63(12):5405-12. doi: 10.1128/JVI.63.12.5405-5412.1989.

本文引用的文献

1
Restricted expression of endogenous N-tropic XC-positive leukemia virus in hybrids between G and AKR mice: an effect of the Fv-4r gene.内源性N-嗜性XC阳性白血病病毒在G和AKR小鼠杂交后代中的限制性表达：Fv-4r基因的作用。
Int J Cancer. 1980 Jun 15;25(6):757-62. doi: 10.1002/ijc.2910250611.
2
Fv-4: gene controlling resistance to NB-tropic Friend murine leukemia virus. Distribution in wild mice, introduction into genetic background of BALB/c mice, and mapping of chromosomes.Fv-4：控制对嗜NB型Friend小鼠白血病病毒抗性的基因。在野生小鼠中的分布、导入BALB/c小鼠的遗传背景以及染色体定位。
J Natl Cancer Inst. 1981 Nov;67(5):1123-7.
3
Friend murine leukemia virus resistance in Japanese wild mice: possible allelism with Fv-4 in FRG mice.日本野生小鼠对Friend鼠白血病病毒的抗性：与FRG小鼠中Fv-4可能的等位性。
J Natl Cancer Inst. 1981 Apr;66(4):729-31.
4
Mapping of the Fv-4 mouse gene controlling resistance to murine leukemia viruses.控制小鼠对鼠白血病病毒抗性的Fv-4小鼠基因的定位
Int J Cancer. 1981 Aug 15;28(2):237-40. doi: 10.1002/ijc.2910280218.
5
Genetic diversity in leukemia-prone feral house mice infected with murine leukemia virus.感染鼠白血病病毒的白血病易感野生家鼠的遗传多样性。
Biochem Genet. 1980 Oct;18(9-10):915-28. doi: 10.1007/BF00500124.
6
Akvr-1, a dominant murine leukemia virus restriction gene, is polymorphic in leukemia-prone wild mice.Akvr-1是一种显性鼠白血病病毒限制基因，在易患白血病的野生小鼠中具有多态性。
Proc Natl Acad Sci U S A. 1980 Jan;77(1):531-5. doi: 10.1073/pnas.77.1.531.
7
Fv-2: identification and location of a second gene governing the spleen focus response to Friend leukemia virus in mice.Fv-2：小鼠中控制对Friend白血病病毒的脾集落反应的第二个基因的鉴定与定位
J Natl Cancer Inst. 1970 Jul;45(1):163-9.
8
A major genetic locus affecting resistance to infection with murine leukemia viruses. 3. Assignment of the Fv-1 locus to linkage group 8 of the mouse.一个影响对鼠白血病病毒感染抗性的主要基因位点。3. 将Fv-1基因位点定位于小鼠的第8连锁群。
J Exp Med. 1973 Mar 1;137(3):850-3. doi: 10.1084/jem.137.3.850.
9
FV-4: a new gene affecting the splenomegaly induction by Friend leukemia virus.FV-4：一个影响弗瑞德白血病病毒诱导脾肿大的新基因。
Jpn J Exp Med. 1975 Dec;45(6):473-8.
10
Isolation of Friend leukemia virus resistant line from non-inbred mouse colony.从非近交系小鼠群体中分离抗Friend白血病病毒品系。
Jpn J Exp Med. 1975 Dec;45(6):467-71.

小鼠逆转录病毒限制基因Fv-4和Akvr-1是单个基因座的等位基因。

Murine retroviral restriction genes Fv-4 and Akvr-1 are alleles of a single locus.

作者信息

O'Brien S J, Berman E J, Estes J D, Gardner M B

出版信息

J Virol. 1983 Sep;47(3):649-51. doi: 10.1128/JVI.47.3.649-651.1983.

DOI:10.1128/JVI.47.3.649-651.1983
PMID:6312088
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC255307/
Abstract

The two murine retroviral restriction genes, Fv-4 and Akvr-1, are very similar in their effects, distributions, ranges of action, and phenotypes. Akvr-1 has been shown to segregate independently in backcrosses with a variety of retroviral restriction loci, including Fv-1, Fv-2, Ril-1, and Ril-2. An allelism test cross of FRG (Fv-4R) X LCRR (Akvr-1R) hybrids mated to AKR mice failed to produce any viremic offspring. These results suggested that Akvr-1R and Fv-4R are alleles of a single locus, Fv-4, on mouse chromosome 12.

摘要

两种小鼠逆转录病毒限制基因Fv-4和Akvr-1在其作用、分布、作用范围和表型方面非常相似。已证明Akvr-1在与包括Fv-1、Fv-2、Ril-1和Ril-2在内的多种逆转录病毒限制位点的回交中独立分离。FRG（Fv-4R）×LCRR（Akvr-1R）杂种与AKR小鼠进行的等位性测交未能产生任何病毒血症后代。这些结果表明Akvr-1R和Fv-4R是小鼠12号染色体上单个位点Fv-4的等位基因。