小鼠逆转录病毒限制基因Fv-4和Akvr-1是单个基因座的等位基因。
Murine retroviral restriction genes Fv-4 and Akvr-1 are alleles of a single locus.
作者信息
O'Brien S J, Berman E J, Estes J D, Gardner M B
出版信息
J Virol. 1983 Sep;47(3):649-51. doi: 10.1128/JVI.47.3.649-651.1983.
Abstract
The two murine retroviral restriction genes, Fv-4 and Akvr-1, are very similar in their effects, distributions, ranges of action, and phenotypes. Akvr-1 has been shown to segregate independently in backcrosses with a variety of retroviral restriction loci, including Fv-1, Fv-2, Ril-1, and Ril-2. An allelism test cross of FRG (Fv-4R) X LCRR (Akvr-1R) hybrids mated to AKR mice failed to produce any viremic offspring. These results suggested that Akvr-1R and Fv-4R are alleles of a single locus, Fv-4, on mouse chromosome 12.
摘要
两种小鼠逆转录病毒限制基因Fv-4和Akvr-1在其作用、分布、作用范围和表型方面非常相似。已证明Akvr-1在与包括Fv-1、Fv-2、Ril-1和Ril-2在内的多种逆转录病毒限制位点的回交中独立分离。FRG（Fv-4R）×LCRR（Akvr-1R）杂种与AKR小鼠进行的等位性测交未能产生任何病毒血症后代。这些结果表明Akvr-1R和Fv-4R是小鼠12号染色体上单个位点Fv-4的等位基因。
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本文引用的文献
1
Restricted expression of endogenous N-tropic XC-positive leukemia virus in hybrids between G and AKR mice: an effect of the Fv-4r gene.
Int J Cancer. 1980 Jun 15;25(6):757-62. doi: 10.1002/ijc.2910250611.
2
3
Friend murine leukemia virus resistance in Japanese wild mice: possible allelism with Fv-4 in FRG mice.
J Natl Cancer Inst. 1981 Apr;66(4):729-31.
4
Mapping of the Fv-4 mouse gene controlling resistance to murine leukemia viruses.
Int J Cancer. 1981 Aug 15;28(2):237-40. doi: 10.1002/ijc.2910280218.
5
Genetic diversity in leukemia-prone feral house mice infected with murine leukemia virus.
Biochem Genet. 1980 Oct;18(9-10):915-28. doi: 10.1007/BF00500124.
6
Akvr-1, a dominant murine leukemia virus restriction gene, is polymorphic in leukemia-prone wild mice.
Proc Natl Acad Sci U S A. 1980 Jan;77(1):531-5. doi: 10.1073/pnas.77.1.531.
7
Fv-2: identification and location of a second gene governing the spleen focus response to Friend leukemia virus in mice.
J Natl Cancer Inst. 1970 Jul;45(1):163-9.
8
A major genetic locus affecting resistance to infection with murine leukemia viruses. 3. Assignment of the Fv-1 locus to linkage group 8 of the mouse.
J Exp Med. 1973 Mar 1;137(3):850-3. doi: 10.1084/jem.137.3.850.
9
FV-4: a new gene affecting the splenomegaly induction by Friend leukemia virus.
Jpn J Exp Med. 1975 Dec;45(6):473-8.
10
Isolation of Friend leukemia virus resistant line from non-inbred mouse colony.
Jpn J Exp Med. 1975 Dec;45(6):467-71.
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