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中间丝基因表达的调控

Regulation of intermediate filament gene expression.

作者信息

Zehner Z E

机构信息

Department of Biochemistry and Molecular Biophysics, Medical College of Virginia, Virginia Commonwealth University, Richmond 23298.

出版信息

Curr Opin Cell Biol. 1991 Feb;3(1):67-74. doi: 10.1016/0955-0674(91)90167-w.

Abstract

Members of the intermediate filament protein family exhibit complex patterns of development-specific and tissue-specific expression. Studies exploring the mechanisms of gene regulation are underway and key regulatory factors are currently being described and isolated for certain genes encoding intermediate filament proteins. Selected systems from this diverse group of about 50 genes will be discussed.

摘要

中间丝蛋白家族成员呈现出复杂的发育特异性和组织特异性表达模式。探索基因调控机制的研究正在进行中,目前正在描述和分离某些编码中间丝蛋白的基因的关键调控因子。将讨论从这一约50个基因的多样化群体中挑选出的系统。

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