Nowalk Mary Patricia, Zimmerman Richard K, Lin Chyongchiou Jeng, Raymund Mahlon, Tabbarah Melissa, Wilson Stephen A, McGaffey Ann, Wahrenberger J Todd, Block Bruce, Hall David G, Fox Dwight E, Ricci Edmund M
Department of Family Medicine and Clinical Epidemiology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, USA.
J Am Geriatr Soc. 2008 Jul;56(7):1177-82. doi: 10.1111/j.1532-5415.2008.01769.x. Epub 2008 Jun 10.
To increase adult immunizations at inner-city health centers serving primarily minority patients.
A before-after trial with a concurrent control.
Five inner-city health centers.
All adult patients at the health centers eligible for influenza and pneumococcal vaccines.
Four intervention sites chose from a menu of culturally appropriate interventions based on the unique features of their respective health centers.
Immunization and demographic data from medical records of a random sample of 568 patients aged 50 and older who had been patients at their health centers since 2000.
The preintervention influenza vaccination rate of 27.1% increased to 48.9% (P<.001) in intervention sites in Year 4, whereas the concurrent control rate remained low (19.7%). The pneumococcal polysaccharide vaccine (PPV) rate in subjects aged 65 and older increased from 48.3% to 81.3% (P<.001) in intervention sites in Year 4. Increase in PPV in the concurrent control was not significant. In logistic regression analysis, the likelihood of influenza vaccination was significantly associated with the intervention (odds ratio (OR)=2.07, 95% confidence interval (CI)=1.77-2.41) and with age of 65 and older (OR=2.0, 95% CI=1.62-2.48) but not with race. Likelihood of receiving the pneumococcal vaccination was also associated with older age and, to a lesser degree, with intervention.
Culturally appropriate, evidence-based interventions selected by intervention sites resulted in increased adult vaccinations in disadvantaged, racially diverse, inner-city populations over 2 to 4 years.
提高主要为少数族裔患者服务的市中心医疗中心的成人疫苗接种率。
前后对照试验并设同期对照。
五个市中心医疗中心。
医疗中心所有符合接种流感疫苗和肺炎球菌疫苗条件的成年患者。
四个干预点根据各自医疗中心的独特特点,从一系列具有文化适宜性的干预措施中进行选择。
从2000年起就在其医疗中心就诊的568名50岁及以上患者的随机样本的医疗记录中获取疫苗接种和人口统计学数据。
在第4年,干预点的干预前流感疫苗接种率从27.1%升至48.9%(P<0.001),而同期对照率仍较低(19.7%)。65岁及以上人群的肺炎球菌多糖疫苗(PPV)接种率在第4年从48.3%升至81.3%(P<0.001)。同期对照中PPV接种率的升高不显著。在逻辑回归分析中,流感疫苗接种的可能性与干预措施显著相关(比值比(OR)=2.07,95%置信区间(CI)=1.77 - 2.41),与65岁及以上年龄也显著相关(OR=2.0,95% CI=1.62 - 2.48),但与种族无关。接受肺炎球菌疫苗接种的可能性也与年龄较大有关,在较小程度上与干预措施有关。
干预点选择的具有文化适宜性、基于证据的干预措施在2至4年内使弱势、种族多样的市中心人群的成人疫苗接种率有所提高。