Klaristenfeld Daniel, Israelit Shlomi, Beart Robert W, Ault Glenn, Kaiser Andreas M
Department of Colorectal Surgery, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, Suite 7418, Los Angeles, CA, 90033, USA.
Int J Colorectal Dis. 2008 Sep;23(9):853-6. doi: 10.1007/s00384-008-0494-0. Epub 2008 Jun 12.
Surgical treatment of extensive and confluent anal condylomata results in large open wounds, which in other contexts of anorectal surgery (e.g., hemorrhoidectomy), have been associated with a relevant risk of stricture formation. The aim of our study was therefore to revisit the issue and assess this risk and the general morbidity in patients undergoing extensive excision and fulguration of anal warts.
Records of 41 consecutive patients undergoing with excision/fulguration of extensive, i.e., >50% confluent anal condylomata were retrospectively reviewed. Excluded were patients with a lesser degree of warts and patients lost to follow-up before complete wound healing. Data recorded included patient characteristics and evolution of the local area after the surgery.
Forty-one patients (40 males and one female) underwent excision and fulguration of a large anal condyloma with an average follow-up of 6 months (range, 1-36 months). The majority of patients (97.6%) were HIV-positive with 80% taking antiretroviral medication. Half of the patients had not received any previous medical or surgical treatment, whereas one fourth had undergone surgical excisions or fulgurations before. Recurrent warts developed in 19 patients (46.3%). The surgical morbidity after the extensive excision consisted of bleeding (22%). However, none of the patients showed any evidence or complaints of postoperative stricturing and anal stenosis at follow-up.
Excision of extensive anal condylomata has a known high probability of recurrences, but the risk of developing anal stenosis is low. Careful primary excision of even confluent warts can therefore be safely performed without major primary flap reconstructions.
广泛融合性肛门尖锐湿疣的手术治疗会导致大面积开放性伤口,在其他肛肠手术(如痔切除术)中,这种伤口与形成狭窄的相关风险有关。因此,我们研究的目的是重新审视这个问题,并评估接受广泛切除和电灼肛门疣患者的这种风险及总体发病率。
回顾性分析41例连续接受广泛(即融合面积>50%)肛门尖锐湿疣切除/电灼术患者的记录。排除疣面积较小的患者以及伤口完全愈合前失访的患者。记录的数据包括患者特征及术后局部区域的演变情况。
41例患者(40例男性,1例女性)接受了大面积肛门尖锐湿疣的切除和电灼术,平均随访6个月(范围1 - 36个月)。大多数患者(97.6%)为HIV阳性,80%正在服用抗逆转录病毒药物。一半患者此前未接受过任何药物或手术治疗,而四分之一患者此前曾接受过手术切除或电灼术。19例患者(46.3%)出现复发性疣体。广泛切除术后的手术并发症包括出血(22%)。然而,随访期间没有患者出现任何术后狭窄和肛门狭窄的证据或主诉。
广泛切除肛门尖锐湿疣复发概率高,但发生肛门狭窄的风险低。因此,即使是融合性疣体,仔细的初次切除也可安全进行,无需进行大型一期皮瓣重建。