Echenique Ignacio, Phillips Benjamin R
Clin Colon Rectal Surg. 2011 Mar;24(1):31-8. doi: 10.1055/s-0031-1272821.
For the last five millennia we have been dealing with the annoyance of verrucas. Anogenital human papillomavirus (HPV) infection is the most common sexually transmitted disease in the United States and is increasing in incidence. As in other gastrointestinal conditions, HPV infection can lead to a stepwise transition from normal cells to dysplastic cells and then to invasive anal cancer. Knowledge of the natural history of HPV infection, risk factors, diagnostic tools, and therapeutic methods gives us the tools to adequately prevent, evaluate, treat, and counsel our patients. In this review, the authors detail the diagnosis, management, and treatment of anal condyloma and anal intraepithelial neoplasia with a focus on prevention, early detection, and treatment using current data and technology.
在过去的五千年里，我们一直在应对疣带来的困扰。肛门生殖器人乳头瘤病毒（HPV）感染是美国最常见的性传播疾病，且发病率正在上升。与其他胃肠道疾病一样，HPV感染可导致细胞从正常逐步转变为发育异常，进而发展为浸润性肛管癌。了解HPV感染的自然史、危险因素、诊断工具和治疗方法，能让我们有足够的手段来预防、评估、治疗患者并为其提供咨询。在这篇综述中，作者详细阐述了肛门尖锐湿疣和肛门上皮内瘤变的诊断、管理及治疗，重点是利用当前数据和技术进行预防、早期检测和治疗。
