Kim Soo Yeon, Yoon Sun, Kwon Soo Mi, Park Kye Sook, Lee-Kim Yang Cha
Graduate School of Human Environmental Science, College of Human Ecology, Yonsei Health Center Yonsei University, 134 Shinchon-dong, Sudaemun-ku, 120-749, Seoul, Korea.
Biomed Environ Sci. 2008 Apr;21(2):91-7. doi: 10.1016/S0895-3988(08)60012-4.
To evaluate the effect of 3-month kale (Brassica oleracea acephala) juice supplementation on coronary artery disease risk factors among hypercholesterolemic men.
Thirty-two men with hypercholesterolemia (> 200 mg/dL) were recruited after annual health examinations among the faculty and staff at university. The subjects consumed 150 mL of kale juice per day for a 12-week intervention period. Dietary and anthropometric assessments were performed and blood samples were collected to evaluate biochemical profiles before and after supplementation.
Serum concentrations of HDL-cholesterol, and HDL- to LDL-cholesterol ratio were significantly increased by 27% (P<0.0001) and 52% (P<0.0001), respectively. The LDL-cholesterol concentration and the atherogenic index were significantly reduced by 10% (P=0.0007) and 24.2% (P<0.0001), respectively without affecting body mass index, waist and hip circumferences, or nutrient intakes after three months of supplementation. While there was no difference in the concentration of malondialdehyde, significant increase in glutathione peroxidase activity (P=0.0005) were accompanied by a significant increase in the serum selenium level (P=0.0132). It was also found that the responses of these risk factors to kale juice administration were dependent on smoking status.
Regular meals supplementation with kale juice can favorably influence serum lipid profiles and antioxidant systems, and hence contribute to reduce the risks of coronary artery disease in male subjects with hyperlipidemia.
评估连续3个月补充羽衣甘蓝（Brassica oleracea acephala）汁对高胆固醇血症男性冠状动脉疾病风险因素的影响。
在大学教职工年度健康检查中招募了32名高胆固醇血症（>200 mg/dL）男性。受试者在为期12周的干预期内每天饮用150 mL羽衣甘蓝汁。在补充前后进行饮食和人体测量评估，并采集血样以评估生化指标。
高密度脂蛋白胆固醇（HDL-胆固醇）血清浓度以及HDL与LDL胆固醇比值分别显著升高27%（P<0.0001）和52%（P<0.0001）。补充3个月后，低密度脂蛋白胆固醇浓度和动脉粥样硬化指数分别显著降低10%（P=0.0007）和24.2%（P<0.0001），且未影响体重指数、腰围和臀围或营养摄入。虽然丙二醛浓度无差异，但谷胱甘肽过氧化物酶活性显著增加（P=0.0005），同时血清硒水平显著升高（P=0.0132）。还发现这些风险因素对羽衣甘蓝汁摄入的反应取决于吸烟状况。
定期在饮食中补充羽衣甘蓝汁可对血清脂质谱和抗氧化系统产生有利影响，从而有助于降低高脂血症男性受试者患冠状动脉疾病的风险。
