[致糖尿病物质对家兔胰岛细胞中锌和钙含量的影响]
[The effect of diabetogenic substances on the zinc and calcium content in the pancreatic islet cells of rabbits].
作者信息
Gol'dberg E D, Eshchenko V A, Bovt V D
出版信息
Biull Eksp Biol Med. 1991 Feb;111(2):135-7.
PMID:1854952
Abstract
The injections of diabetogenic drugs to rabbits induced a decrease in zinc and calcium content in B insulocytes dependent on the degree of these cells damage and hyperglycemia. The content of these metals in A insulocytes was not significantly altered due to a light injury of these cells. A high concentration of calcium in islet A cells is suggested to be a protective factor to the action of alteration agents.
摘要
给兔子注射致糖尿病药物会导致胰岛B细胞中的锌和钙含量降低，这取决于这些细胞的损伤程度和高血糖水平。由于胰岛A细胞受到轻度损伤，这些金属在其中的含量没有明显变化。胰岛A细胞中高浓度的钙被认为是对抗改变剂作用的一种保护因素。
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