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[致糖尿病物质对家兔胰岛细胞中锌和钙含量的影响]

[The effect of diabetogenic substances on the zinc and calcium content in the pancreatic islet cells of rabbits].

作者信息

Gol'dberg E D, Eshchenko V A, Bovt V D

出版信息

Biull Eksp Biol Med. 1991 Feb;111(2):135-7.

PMID:1854952
Abstract

The injections of diabetogenic drugs to rabbits induced a decrease in zinc and calcium content in B insulocytes dependent on the degree of these cells damage and hyperglycemia. The content of these metals in A insulocytes was not significantly altered due to a light injury of these cells. A high concentration of calcium in islet A cells is suggested to be a protective factor to the action of alteration agents.

摘要

给兔子注射致糖尿病药物会导致胰岛B细胞中的锌和钙含量降低,这取决于这些细胞的损伤程度和高血糖水平。由于胰岛A细胞受到轻度损伤,这些金属在其中的含量没有明显变化。胰岛A细胞中高浓度的钙被认为是对抗改变剂作用的一种保护因素。

相似文献

1
[The effect of diabetogenic substances on the zinc and calcium content in the pancreatic islet cells of rabbits].[致糖尿病物质对家兔胰岛细胞中锌和钙含量的影响]
Biull Eksp Biol Med. 1991 Feb;111(2):135-7.
2
[The dynamics of the Zn content in the pancreatic islets of rabbits after the administration of the diabetogenic agent dithizone].[给予致糖尿病剂双硫腙后家兔胰岛中锌含量的动态变化]
Patol Fiziol Eksp Ter. 1991 Jul-Aug(4):43-5.
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[Zinc contents of pancreatic islets in animals of various species after administration of diabetogenic agent, dithizone].[给予致糖尿病药物双硫腙后不同物种动物胰岛的锌含量]
Biull Eksp Biol Med. 1992 Jan;113(1):53-5.
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[The effect of cyclosporin A on the islet cells of mice].[环孢素A对小鼠胰岛细胞的作用]
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Primary insulin insufficiency after blocking of zinc in pancreatic beta-cells.胰腺β细胞中锌被阻断后原发性胰岛素分泌不足。
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[Zinc content of pancreatic islets in diabetes].[糖尿病患者胰岛的锌含量]
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Preventive effect of diethyldithiocarbamate on experimental diabetes produced by dithisone and 8-oxychinoline.二乙基二硫代氨基甲酸盐对由双硫腙和8-羟基喹啉所致实验性糖尿病的预防作用
Endocrinol Exp. 1979 Mar;13(1):39-51.