Dundee J W, Ghaly G
Department of Anaesthetics, Queen's University of Belfast, Northern Ireland.
Clin Pharmacol Ther. 1991 Jul;50(1):78-80. doi: 10.1038/clpt.1991.106.
The incidence of postoperative illness was monitored for 6 hours in 74 women premedicated with nalbuphine, 10 mg, and undergoing short gynecologic operations of similar duration under methohexitalnitrous oxide-oxygen anesthesia. Each patient received P6 acupuncture for 5 minutes at the time of administration of premedication. In random order the site of the acupuncture had been previously infiltrated with normal saline solution in half of the patients and 1% lidocaine in the remaining patients. Postoperative emetic sequelae occurred significantly more often in those who received lidocaine compared with the group that received saline solution. This demonstrates the ability of a local anesthetic administered at the point of stimulation to block the antiemetic action of P6 acupuncture in a manner similar to that shown by others for analgesia.
对74名接受10毫克纳布啡预处理、在美索比妥 - 氧化亚氮 - 氧气麻醉下进行类似时长短妇科手术的女性，术后疾病发生率进行了6小时监测。每位患者在给予预处理药物时接受5分钟的内关穴针刺。一半患者的针刺部位先前已用生理盐水浸润，其余患者则用1%利多卡因浸润，顺序随机。与接受生理盐水的组相比，接受利多卡因的患者术后呕吐后遗症发生得更频繁。这表明在刺激点给予局部麻醉药能够以类似于其他人所展示的镇痛方式阻断内关穴针刺的止吐作用。
