伊朗伊斯兰共和国纳哈万德戊型肝炎血清流行率：一项基于人群的研究。

Seroprevalence of hepatitis E in Nahavand, Islamic Republic of Iran: a population-based study.

作者信息

Taremi M, Mohammad Alizadeh A H, Ardalan A, Ansari S, Zali M R

机构信息

Research Centre for Gastroenterology and Liver Diseases, Shaheed Beheshti University of Medical Sciences, Tehran, Islamic Republic of Iran.

出版信息

East Mediterr Health J. 2008 Jan-Feb;14(1):157-62.

PMID:18557463

Abstract

A 2-month community-based survey in February/March of 2003 was carried out to study the seroprevalence of hepatitis E virus (HEV) infection in Nahavand, Islamic Republic of Iran. From each of 6 urban regions of Nahavand, 304 inhabitants > or = 6 years were recruited through systematic random sampling (total 1824). Participants were tested for anti-HEV IgG using ELISA. The overall seroprevalence of HEV was 9.3% (95% CI: 8.2%-10.9%). Based on multivariate adjustment, only sex (OR = 1.61, 95% CI: 1.13-2.28) and age (OR = 1.03, 95% CI: 1.01-1.04) emerged as significant risk factors. This intermediate prevalence urges further investigations on HEV infection in the Islamic Republic of Iran.

摘要

2003年2月/3月开展了一项为期2个月的基于社区的调查，以研究伊朗伊斯兰共和国纳哈万德戊型肝炎病毒（HEV）感染的血清流行率。通过系统随机抽样，从纳哈万德的6个城市区域各招募了304名6岁及以上居民（共1824人）。采用酶联免疫吸附测定法（ELISA）对参与者进行抗HEV IgG检测。HEV的总体血清流行率为9.3%（95%置信区间：8.2%-10.9%）。经过多变量调整后，只有性别（比值比=1.61，95%置信区间：1.13-2.28）和年龄（比值比=1.03，95%置信区间：1.01-1.04）是显著的危险因素。这种中等流行率促使对伊朗伊斯兰共和国的HEV感染进行进一步调查。