Khanna Nitish
Department of Microbiology, Western Infirmary, Dumbarton Road, Glasgow G11 6NT, United Kingdom.
J Tissue Viability. 2008 Aug;17(3):95-7. doi: 10.1016/j.jtv.2008.04.001. Epub 2008 Jun 16.
Clostridium perfringens is responsible for a number of clinical conditions ranging from relatively mild food poisoning to the potentially life-threatening gas gangrene. Fortunately, C. perfringens has remained relatively susceptible to first line antibiotics in the treatment of soft tissue infection, however, the prevalence of antibiotic resistance is increasing amongst other anaerobic organisms. A case of anaerobic cellulitis caused by a clindamycin-resistant C. perfringens is described here, emphasising the emerging problem of antimicrobial resistance.
产气荚膜梭菌可引发多种临床病症，从相对轻微的食物中毒到可能危及生命的气性坏疽。幸运的是，在软组织感染的治疗中，产气荚膜梭菌对一线抗生素仍相对敏感，然而，其他厌氧生物中的抗生素耐药性患病率正在上升。本文描述了一例由耐克林霉素的产气荚膜梭菌引起的厌氧性蜂窝织炎病例，强调了抗菌药物耐药性这一新兴问题。
