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烟曲霉分泌的18千道尔顿抗原。

The 18-kilodalton antigen secreted by Aspergillus fumigatus.

作者信息

Latgé J P, Moutaouakil M, Debeaupuis J P, Bouchara J P, Haynes K, Prévost M C

机构信息

Unité de Mycologie, Institut Pasteur, Paris, France.

出版信息

Infect Immun. 1991 Aug;59(8):2586-94. doi: 10.1128/iai.59.8.2586-2594.1991.

DOI:10.1128/iai.59.8.2586-2594.1991
PMID:1855978
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC258060/
Abstract

One of the major antigens secreted in vitro by Aspergillus fumigatus is an 18-kDa basic protein which has been purified by cation-exchange chromatography. It is recognized by sera from aspergilloma patients. It is also the major circulating antigen found in urine of patients with invasive aspergillosis. Our results indicated that this antigen has potential for the diagnosis of both aspergilloma and invasive aspergillosis.

摘要

烟曲霉在体外分泌的主要抗原之一是一种18 kDa的碱性蛋白，该蛋白已通过阳离子交换色谱法纯化。曲霉肿患者的血清可识别该蛋白。它也是侵袭性曲霉病患者尿液中发现的主要循环抗原。我们的结果表明，这种抗原在曲霉肿和侵袭性曲霉病的诊断中具有潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3ae/258060/863ae177bac2/iai00044-0088-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3ae/258060/3f97efb40bc9/iai00044-0084-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3ae/258060/28f225427bca/iai00044-0084-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3ae/258060/a36f0f46b8c6/iai00044-0085-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3ae/258060/13e504544a7f/iai00044-0088-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3ae/258060/863ae177bac2/iai00044-0088-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3ae/258060/3f97efb40bc9/iai00044-0084-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3ae/258060/28f225427bca/iai00044-0084-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3ae/258060/a36f0f46b8c6/iai00044-0085-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3ae/258060/13e504544a7f/iai00044-0088-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3ae/258060/863ae177bac2/iai00044-0088-b.jpg

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