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伤寒疫苗接种:亚洲的经验。

Typhoid vaccination: the Asian experience.

作者信息

DeRoeck Denise, Ochiai R Leon, Yang Jin, Anh Dang Duc, Alag Vibha, Clemens John D

机构信息

Social Science Research and Institutional Development, International Vaccine Institute, San 4-8 Bongcheon-7-Dong, Kwanak-Gu, Seoul 151-818, Republic of Korea.

出版信息

Expert Rev Vaccines. 2008 Jul;7(5):547-60. doi: 10.1586/14760584.7.5.547.

DOI:10.1586/14760584.7.5.547
PMID:18564010
Abstract

The WHO has recently issued updated recommendations for the programmatic use of new-generation typhoid vaccines in high-risk areas of countries where typhoid fever is still endemic. Countries have subsequently been instructed to discuss how these recommendations can be implemented and to develop plans for targeted typhoid vaccination. These plans can be informed by the experiences with typhoid vaccination that several Asian countries have had. This article reviews past and current typhoid vaccination programs that have taken place in Thailand (using the old whole-cell vaccine) and in China, Vietnam and India (using the new-generation injectable Vi polysaccharide vaccine). This review also describes recent typhoid Vi vaccine demonstration projects that were conducted in five Asian countries.

摘要

世界卫生组织最近发布了关于在伤寒热仍然流行的国家的高风险地区按计划使用新一代伤寒疫苗的最新建议。随后,各国接到指示,讨论如何实施这些建议,并制定针对性伤寒疫苗接种计划。这些计划可参考几个亚洲国家在伤寒疫苗接种方面的经验。本文回顾了泰国(使用旧的全细胞疫苗)以及中国、越南和印度(使用新一代注射用Vi多糖疫苗)过去和当前的伤寒疫苗接种项目。本综述还介绍了最近在五个亚洲国家开展的伤寒Vi疫苗示范项目。

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