Müller Cornelia S L, Pföhler Claudia, Tilgen Wolfgang
Department of Dermatology, The Saarland University Hospital, Homburg/Saar, Germany.
J Cutan Pathol. 2009 Jan;36(1):44-8. doi: 10.1111/j.1600-0560.2008.00995.x. Epub 2008 Jun 17.
Galli-Galli disease (GGD) and Dowling-Degos disease (DDD) are inherited skin diseases with variable progressive course. They are of benign and harmless behaviour but aesthetically annoying. They are subsumed within the group of reticulate pigmented disorders of the skin to which, additionally, Kitamura's and Haber's diseases are counted. Clinical appearance is approximately similar, with slight differences in age of onset and associated disorders. Histopathological features are almost similar aside from the unique hallmark of suprabasal acantholysis, which can exclusively be observed in GGD. We report four typical cases of reticulate pigmented disorders, clinically accordable to DDD but histopathologically allocated to GGD. In conclusion, we purpose the idea of a wide spectrum of reticulate pigmented disorders in which Morbus Galli-Galli should probably be reclassified as a subset of DDD.
加利-加利病（GGD）和道林-德戈斯病（DDD）是具有不同进展过程的遗传性皮肤病。它们表现为良性且无害，但在美观上令人烦恼。它们被归入皮肤网状色素沉着性疾病组，此外，北村病和哈伯病也属于该组。临床表现大致相似，仅在发病年龄和相关病症上有细微差异。除了在基底层上棘层松解这一仅在GGD中可观察到的独特特征外，组织病理学特征几乎相似。我们报告了4例网状色素沉着性疾病的典型病例，临床诊断符合DDD，但组织病理学诊断为GGD。总之，我们提出了一种广泛的网状色素沉着性疾病的概念，其中加利-加利病可能应重新归类为DDD的一个亚型。
