Eventov-Friedman S, Shinwell E S
Department of Neonatology, Kaplan Medical Center, Rehovot and Hebrew University, Jerusalem, Israel.
Acta Paediatr. 2008 Nov;97(11):1492-501. doi: 10.1111/j.1651-2227.2008.00907.x. Epub 2008 Jun 19.
Few therapies in perinatal medicine have created as much controversy as corticosteroids. Despite five decades of extensive research and practice, major areas of uncertainty remain. In this article, we review the most current evidence on both antenatal and postnatal therapy.
Overall, it is clear that we must continue to investigate the most appropriate doses of the ideal preparation in the most appropriate target populations before we can let the steroid issues rest.
围产期医学中很少有疗法像皮质类固醇那样引发如此多的争议。尽管经过了五十年的广泛研究和实践,但仍存在主要的不确定性领域。在本文中,我们回顾了关于产前和产后治疗的最新证据。
总体而言,很明显在我们能让类固醇问题平息之前,必须继续研究在最合适的目标人群中使用理想制剂的最合适剂量。