Chen Ji-An, Liu Huijie, Qiu Zhiqun, Shu Weiqun
Department of Environmental Hygiene, School of Preventive Medicine, Third Military Medical University, Chongqing 400038, China.
Environ Pollut. 2008 Dec;156(3):849-53. doi: 10.1016/j.envpol.2008.05.019. Epub 2008 Jun 18.
In this study, 40 healthy women from Chongqing undergoing parturition were recruited and samples of venous blood, umbilical cord blood, breast milk and urine were collected for analysis of organic pollutants by GC/MS. A total of 292 different organic pollutants were detected, including 156 in venous blood, 139 in umbilical cord blood, 176 in breast milk and 138 in urine. Nine different PAEs were detectable in the samples: di-n-butyl phthalate (DBP), bis(2-methylpropyl) phthalate, butyl-8-methyl-nonyl phthalate, di-ethyl phthalate, butyl-2-methylpropyl phthalate, butyloctyl phthalate, di-dodecyl phthalate, di-isodecyl phthalate, and di-tridecyl phthalate. DBP was one of the chemicals detected at the highest frequency (48.82%). DBP concentrations were 84.75+/-33.52, 52.23+/-32.50, 57.78+/-35.42 and 24.93+/-18.67 microg/l in venous blood, umbilical cord blood, breast milk and urine, respectively. This study represents the first investigation of organic pollutants in a Chongqing population.
在本研究中，招募了40名来自重庆的健康产妇，并采集了她们的静脉血、脐带血、母乳和尿液样本，通过气相色谱/质谱联用仪（GC/MS）分析其中的有机污染物。共检测到292种不同的有机污染物，其中静脉血中检测到156种，脐带血中检测到139种，母乳中检测到176种，尿液中检测到138种。样本中可检测到9种不同的邻苯二甲酸酯：邻苯二甲酸二丁酯（DBP）、邻苯二甲酸二异丁酯、邻苯二甲酸丁基-8-甲基壬酯、邻苯二甲酸二乙酯、邻苯二甲酸丁基-2-甲基丙酯、邻苯二甲酸丁基辛酯、邻苯二甲酸二正十二酯、邻苯二甲酸二异癸酯和邻苯二甲酸二正十三酯。DBP是检测频率最高的化学物质之一（48.82%）。静脉血、脐带血、母乳和尿液中DBP的浓度分别为84.75±33.52、52.23±32.50、57.78±35.42和24.93±18.67微克/升。本研究是对重庆人群有机污染物的首次调查。
