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茶树红茶冲泡液对雄性大鼠性能力的影响。

Effect of black tea brew of Camellia sinensis on sexual competence of male rats.

作者信息

Ratnasooriya W D, Fernando T S P

机构信息

Department of Zoology, University of Colombo, Colombo 03, Sri Lanka.

出版信息

J Ethnopharmacol. 2008 Aug 13;118(3):373-7. doi: 10.1016/j.jep.2008.04.023. Epub 2008 May 4.

Abstract

AIM

In Sri Lankan traditional medicine black tea brew (BTB) of Camellia sinensis (L.) O. Kuntze (Theaceae) is claimed to have male sexual stimulant activity. As this claim is not scientifically tested and proven, this study was undertaken to evaluate the effects of BTB on male sexual competence.

MATERIAL AND METHODS

Different doses of BTB made from Sri Lankan high grown dust grade no 1 tea (84, 167 and 501 mg/ml) or water were orally administered to separate groups of rats (n=9 per group) and 3h later their sexual behaviour were monitored (for 15 min) using receptive females.

RESULTS

The overall results showed that BTB possesses marked aphrodisiac activity (in terms of prolongation of latency of ejaculation shortening of mount- and intromission latencies and elevation of serum testosterone level). The aphrodisiac action had a rapid onset and appears to be mediated via inhibition of anxiety and elevation of serum testosterone level. Further, this aphrodisiac action was not associated with impairment of other sexual parameters like libido, sexual motivation, sexual arousal, sexual vigour or penile erection. BTB was also nontoxic (in terms of overt signs, liver and renal toxicity).

CONCLUSIONS

It is concluded that BTB can function as a quick acting, safe, oral aphrodisiac which may also be useful in certain forms of sexual inadequacies such as premature ejaculation and impaired libido and other sexual functions.

摘要

目的

在斯里兰卡传统医学中,茶树(山茶科)的红茶冲泡液(BTB)据称具有男性性刺激活性。由于这一说法未经科学测试和证实,因此开展本研究以评估BTB对男性性能力的影响。

材料与方法

将不同剂量由斯里兰卡高海拔1号茶粉制成的BTB(84、167和501毫克/毫升)或水经口给予不同组的大鼠(每组n = 9),3小时后使用处于接受状态的雌性大鼠监测它们的性行为(持续15分钟)。

结果

总体结果表明,BTB具有显著的催情活性(表现为射精潜伏期延长、爬跨和插入潜伏期缩短以及血清睾酮水平升高)。催情作用起效迅速,似乎是通过抑制焦虑和提高血清睾酮水平介导的。此外,这种催情作用与其他性参数如性欲、性动机、性唤起、性活力或阴茎勃起的损害无关。BTB也是无毒的(就明显体征、肝脏和肾脏毒性而言)。

结论

得出的结论是,BTB可作为一种速效、安全的口服催情剂,可能对某些形式的性能力不足如早泄、性欲减退和其他性功能障碍也有用。

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