Jalava-Broman Jaana, Mäkinen Juha, Ojanlatva Ansa, Jokinen Kirsi, Sillanmäki Lauri, Rautava Päivi
Department of Public Health, University of Turku, Finland.
Acta Obstet Gynecol Scand. 2008;87(6):682-6. doi: 10.1080/00016340802146920.
To examine the use of hormone therapy (HT) or alternative treatments for climacteric symptoms among women aged 52-56 years in 2000.
Questionnaire study.
Cross-sectional Finnish female cohort in the year 2000.
Random sample of women aged 52-56 years.
Univariate and multivariate analysis.
HT explained by 12 physical and 9 background and social variables.
The use of HT was significantly (p<0.001) associated with the severity of climacteric symptoms, a history of not having breast cancer, oophorectomy, low body mass index, high professional education and high alcohol intake. A total of 66% of the women used some form of treatment for their climacteric symptoms. Of them, 71% used systemic HT, 25% alternative treatments (hypnotics, antidepressants, tranquillizers, trace elements, vitamins, lifestyle modifications) and 4% local estrogens only. Altogether 33% of the women with severe climacteric symptoms did not use HT at all, whereas 27% without any symptoms used HT.
In early 2000, almost half of the Finnish female population at menopause used HT to alleviate their climacteric symptoms. The impact of the controversial reports on HT use after the time of data collection needs further study.
研究2000年52 - 56岁女性使用激素疗法（HT）或其他替代疗法治疗更年期症状的情况。
问卷调查研究。
2000年芬兰女性横断面队列研究。
52 - 56岁女性的随机样本。
单因素和多因素分析。
由12项身体指标以及9项背景和社会变量来解释HT的使用情况。
HT的使用与更年期症状的严重程度、无乳腺癌病史、卵巢切除术、低体重指数、高学历以及高酒精摄入量显著相关（p<0.001）。共有66%的女性采用了某种形式的治疗来缓解更年期症状。其中，71%使用全身HT，25%使用替代疗法（催眠药、抗抑郁药、镇静剂、微量元素、维生素、生活方式改变），4%仅使用局部雌激素。在有严重更年期症状的女性中，共有33%根本未使用HT，而在无症状的女性中，有27%使用了HT。
在2000年初，几乎一半处于更年期的芬兰女性使用HT来缓解更年期症状。在数据收集之后，关于HT使用的争议性报告所产生的影响尚需进一步研究。
