Xuefeng Qi, Xiaoyan Yang, Anchun Cheng, Mingshu Wang, Dekang Zhu, Renyong Jia
Avian Disease Research Center, College of Veterinary Medicine of Sichuan Agricultural University, Ya'an, Sichuan, China.
Avian Pathol. 2008 Jun;37(3):307-10. doi: 10.1080/03079450802043775.
Duck virus enteritis is an acute and contagious herpesvirus infection of duck, geese and swans with high morbidity and mortality. The kinetics of viral DNA loads and immunohistochemical localization of virulent duck enteritis virus, as well as histopathological examination in various tissues of ducks following oral infection, were investigated. The time course for the appearance of viral antigen and tissue lesions in various tissues was coincident with the levels of duck enteritis virus at the various sites, suggesting that the levels of duck enteritis virus in systemic organs have a close correlation with the progression of disease. The abundance of target epithelial and lymphoid cells may contribute to the high levels of virus infection and replication in lymphoid and intestinal tissues.
鸭病毒性肠炎是一种鸭、鹅和天鹅的急性传染性疱疹病毒感染，发病率和死亡率很高。研究了强毒鸭肠炎病毒的病毒DNA载量动力学、免疫组织化学定位，以及口服感染后鸭各组织的组织病理学检查。各组织中病毒抗原和组织病变出现的时间进程与各部位鸭肠炎病毒水平一致，表明全身器官中鸭肠炎病毒水平与疾病进展密切相关。靶上皮细胞和淋巴细胞的丰度可能导致病毒在淋巴组织和肠道组织中高水平感染和复制。
