Hill Haley D, Macfarlane Robert J, Senesi Andrew J, Lee Byeongdu, Park Sung Yong, Mirkin Chad A
Department of Chemistry and International Institute for Nanotechnology, Northwestern University, Evanston, Illinois 60208-3113, USA.
Nano Lett. 2008 Aug;8(8):2341-4. doi: 10.1021/nl8011787. Epub 2008 Jun 24.
DNA-functionalized gold nanoparticles can be used to induce the formation and control the unit cell parameters of highly ordered face-centered cubic crystal lattices. Nanoparticle spacing increases linearly with longer DNA interconnect length, yielding maximum unit cell parameters of 77 nm and 0.52% inorganic-filled space for the DNA constructs studied. In general, we show that longer DNA connections result in a decrease in the overall crystallinity and order of the lattice due to greater conformational flexibility.
DNA功能化的金纳米颗粒可用于诱导高度有序的面心立方晶格的形成并控制其晶胞参数。纳米颗粒间距随DNA互连长度的增加而线性增加,对于所研究的DNA构建体,产生的最大晶胞参数为77 nm,无机填充空间为0.52%。一般来说,我们表明,由于更大的构象灵活性,更长的DNA连接会导致晶格的整体结晶度和有序度降低。