Smirnov I V, Tseneva G Ia, Mitrikova L A
Mol Gen Mikrobiol Virusol. 1991 Mar(3):19-21.
The dispersion of plasmid pYV associated virulence markers in 474 Yersinia strains isolated from people has been studied. The ability to autoagglutination, calcium dependence of growth and the specific antigens were identified in 157 strains of traditionally pathogenic Yersinia enterocolitica serovars 03, 09, Yersinia pseudotuberculosis serovar I. They were not found in 223 strains of other 12 serovars of Yersinia enterocolitica, in 40 strains of Yersinia frederiksenii, Yersinia kristensenii, Yersinia intermedia. The proportion of virulent clones in the population of Yersinia is noted to depend on the conditions of its existence in vivo or in vitro. Identification of virulence markers is acknowledged to be expedient in epidemiological and ethiological estimation of the role of isolated Yersinia strains.
对从人分离出的474株耶尔森氏菌中与毒力相关的质粒pYV标记物的分散情况进行了研究。在157株传统致病性小肠结肠炎耶尔森氏菌血清型03、09、假结核耶尔森氏菌血清型I中鉴定出了自凝能力、生长对钙的依赖性和特异性抗原。在小肠结肠炎耶尔森氏菌其他12个血清型的223株菌株、弗氏耶尔森氏菌40株、克氏耶尔森氏菌、中间耶尔森氏菌中未发现这些特性。耶尔森氏菌群体中毒力克隆的比例取决于其在体内或体外的生存条件。在对分离出的耶尔森氏菌菌株的作用进行流行病学和病因学评估时,鉴定毒力标记物被认为是合适的。