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[异种辐射嵌合体腹腔中包裹异物的细胞的骨髓起源]

[The bone marrow origin of the cells encapsulating a foreign body in the peritoneal cavity of xenogeneic radiation chimeras].

作者信息

Michurina T V, Satdykova G P, Voskresenskiĭ D K, Gauze L N, Chekunova A I, Khrushchov N G

出版信息

Ontogenez. 1991 Jan-Feb;22(1):76-83.

PMID:1857589
Abstract

The origin and ultrastructure of the cells, encapsulating foreign body in peritoneal cavity of xenogeneic (rat in mouse) radiation chimeras was studied. The donor nature of the cells was identified by their karyotype and by DNA hybridization with rat ID-element. Cells with ultrastructural characteristics of fibroblasts encapsulating foreign body in the peritoneal cavity of the xenogeneic radiation chimeras were shown to originate from the transplanted (donor) bone marrow.

摘要

研究了异种(小鼠体内的大鼠)辐射嵌合体腹腔中包裹异物的细胞的起源和超微结构。通过细胞的核型以及与大鼠ID元件的DNA杂交来鉴定细胞的供体性质。结果表明,在异种辐射嵌合体腹腔中包裹异物的具有成纤维细胞超微结构特征的细胞起源于移植的(供体)骨髓。

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