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[正常条件下及无菌性炎症中异种辐射嵌合体结缔组织细胞起源的免疫荧光研究]

[Immunofluorescent study of the origin of connective tissue cells in xenogenic radiation chimeras under normal conditions and in aseptic inflammation].

作者信息

Vasil'eva T V, Michurina T V, Khrushchov N G

出版信息

Ontogenez. 1978;9(3):288-90.

PMID:353618
Abstract

The origin of elements of the focus of aseptic inflammation and the normal subcutaneous connective tissue in the xenogenic (mouse-rat) radiation chimaeras was investigated by means of indirect Coons method with antiserum to the rat bone marrow cells. The cells of the imflammation focus (leucocytes, macrophages, fibroblasts or fibroblast-like cells, polynuclear giant cells of foreign bodies), as well as leucocytes, macrophages and some fibroblasts of the normal subcutaneous connective tissue, were shown to take their origin from the transplanted bone marrow cells of the donor.

摘要

采用间接库恩斯法,使用抗大鼠骨髓细胞抗血清,研究了异种(小鼠 - 大鼠)辐射嵌合体中无菌性炎症灶和正常皮下结缔组织成分的起源。结果显示,炎症灶中的细胞(白细胞、巨噬细胞、成纤维细胞或成纤维样细胞、异物多核巨细胞),以及正常皮下结缔组织中的白细胞、巨噬细胞和一些成纤维细胞,均起源于供体移植的骨髓细胞。

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