Uyeda Christopher, Jacobsen Eric N
Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, Massachusetts 02138, USA.
J Am Chem Soc. 2008 Jul 23;130(29):9228-9. doi: 10.1021/ja803370x. Epub 2008 Jun 25.
N,N'-Diphenylguanidinium ion associated with the noncoordinating BArF counterion is shown to be an effective catalyst for the [3,3]-sigmatropic rearrangement of a variety of substituted allyl vinyl ethers. Highly enantioselective catalytic Claisen rearrangements of ester-substituted allyl vinyl ethers are then documented using a new C2-symmetric guanidinium ion derivative.
与非配位的BArF抗衡离子相关联的N,N'-二苯基胍离子被证明是多种取代烯丙基乙烯基醚进行[3,3] - 迁移重排的有效催化剂。随后,使用一种新的C2对称胍离子衍生物记录了酯取代烯丙基乙烯基醚的高度对映选择性催化克莱森重排反应。